39082-40-1

Basic information

• Product Name: 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE
• Synonyms: 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE;1-Methoxy-4-[(4-nitrophenyl)ethynyl]benzene;4-[(4-Nitrophenyl)ethynyl]anisole
• CAS NO: 39082-40-1
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.25274
• Mol File: 39082-40-1.mol
• Article Data: 56

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE(39082-40-1)
• EPA Substance Registry System: 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE(39082-40-1)

Safety Data

• Hazardous Substances Data: 39082-40-1(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxyphenyl)-2-(4-nitrophenyl)-acetylene is a chemical compound with the molecular formula C16H11NO3. It is commonly used as an intermediate in the synthesis of various organic compounds and pharmaceuticals. 1-(4-METHOXYPHENYL)-2-(4-NITROPHENYL)-ACETYLENE is a derivative of phenylacetylene, and its structure consists of a phenyl group substituted with a methoxy group and a nitro group. It is a yellow crystalline solid that is sparingly soluble in water but more soluble in organic solvents. It is important to handle this compound with caution as it can pose health and environmental hazards if not handled properly.

Upstream product

• 54335-03-4 diphenyl phosphonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 586-78-7 para-nitrophenyl bromide 
• 768-60-5 4-methoxyphenylacetylen 
• 1237789-51-3 C₁₄H₁₄BNO₅ 
• 3989-14-8 (4-methoxyphenylethynyl)trimethylsilane 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 100-00-5 4-chlorobenzonitrile 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 17763-80-3 para-nitrophenyl triflate 
• 555-16-8 4-nitrobenzaldehdye 
• 636-98-6 p-nitrobenzene iodide 
• 60512-57-4 1-(2,2-dibromovinyl)-4-methoxybenzene 
• 937-31-5 (4-Nitrophenyl)acetylene 

Downstream Products

• 6302-84-7 2-(4-methoxyphenyl)-4,5-dihydro-1H-imidazole 
• 99-99-0 1-methyl-4-nitrobenzene 
• 18938-22-2 4-((4-nitrophenyl)ethynyl)phenol 
• 1621074-26-7 C₄₁H₃₀N₂O₈S 
• 1584633-36-2 1-acetyl-6-(4-methoxyphenyl)-5-(4-nitrophenyl)pyridin-2(1H)-one 

Relevant articles and documents

A New Organic Material Exhibiting Highly Efficient Phase-matched Second Harmonic Generation: 4-Methoxy-4'-nitrotolan

The high second harmonic efficiency with phase-matchable characteristics of a new nonlinear optical material, 4-methoxy-4'-nitrotolan, is reported.

Atom-Economical Thiocyanation-Amination of Alkynes with N-Thiocyanato-Dibenzenesulfonimide

A highly regioselective protocol for intermolecular thiocyanation-amination of alkynes by N-thiocyano-dibenzenesulfonimide (NTSI) as the SCN and nitrogen sources has been developed. A C-S bond and C-N bond are simultaneously constructed in only one step. The reaction under simple mild conditions features a broad substrate scope, atom economy, high yields (up to 94%), and excellent functional group tolerance.

Magnetic chitosan-functionalized cobalt-NHC: Synthesis, characterization and catalytic activity toward Suzuki and Sonogashira cross-coupling reactions of aryl chlorides

Aryl chlorides are one of the most stable and available electrophiles, however, their coupling with nucleophiles remains a challenge in organic synthesis. Herein, we prepared a Cobalt-NHC (N-Heterocyclic carbene) complex anchored on magnetic chitosan nanoparticles and assayed its catalytic activity for the reactions of substituted phenylboronic acid and also phenlacetylene with derivatives of aryl chlorides. These reactions are of great importance since they are employed for the synthesis of unsymmetrical diarylethynes and biphenyls, which belong to a prime class of building blocks. The synthesized nanocatalyst was found to be highly efficient in Suzuki and Sonogashira coupling in terms of their activity and recyclability in polyethylene glycol (PEG) as a green reaction media under conditions of temperatures (70 and 100 °C) and Co loading (3 and 6 mol%). To the best of our knowledge, this is the first attempt of using cobalt-NHC complex for catalyzing the abovementioned reactions. Moreover, replacing the earth-abundant Cobalt-based catalyst as an alternative to high cost palladium make this approach promising from sustainable chemistry view.