29478-39-5

Basic information

• Product Name: 1-Octen-3-one, 1-phenyl-, (1E)-
• CAS NO: 29478-39-5
• Molecular Formula: C14H18O
• Molecular Weight: 202.296
• Mol File: 29478-39-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: 1-Octen-3-one, 1-phenyl-, (1E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Octen-3-one, 1-phenyl-, (1E)-(29478-39-5)
• EPA Substance Registry System: 1-Octen-3-one, 1-phenyl-, (1E)-(29478-39-5)

Safety Data

• Hazardous Substances Data: 29478-39-5(Hazardous Substances Data)

Upstream product

• 19969-14-3 2-methyl-5-pentyl-3-phenyl-isoxazolidine 
• 591-50-4 iodobenzene 
• 4312-99-6 oct-1-en-3-one 
• 108-86-1 bromobenzene 
• 110-43-0 n-pentyl methyl ketone 
• 100-52-7 benzaldehyde 
• 14371-10-9 (E)-3-phenylpropenal 
• 693-25-4 n-pentylmagnesium bromide 
• 909413-25-8 6-(tert-butyl)-12-phenyl-5,6,7,12-tetrahydrodibenzo[c,f][1,5]azastibocine 
• 142-61-0 Hexanoyl chloride 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 62059-61-4 1-phenyl-1-octyn-3-one 
• 16339-93-8 1-bromoheptan-2-one 
• 3391-86-4 1-octen-3-ol 

Downstream Products

• 6047-99-0 1-phenyloctan-3-one 
• 888224-92-8 (2Z)-1-(2-furyl)-2-phenyl-2-nonene-1,4-dione 
• 104995-81-5 E-(S)-(+)-1-phenyloct-1-en-3-ol 
• 29494-47-1 1-Phenyl-2-benzyl-3-octanon 
• 1992-49-0 1-phenyl-3-octanol 
• 176588-41-3 (E)-1-phenyl-1-octen-3-ol 
• 143111-94-8 4-butyl-5-dimethylamino-1-phenyl-1-penten-3-one hydrochloride 
• 29494-48-2 2-butyl-4-hexanoyl-3,5-diphenyl-cyclohexanone 

Relevant articles and documents

Mizoroki-Heck Reaction of Unstrained Aryl Ketones via Ligand-Promoted C-C Bond Olefination

Mizoroki-Heck reaction of unstrained aryl ketone with acrylate/styrene is accomplished via palladium-catalyzed ligand-promoted C-C bond cleavage. Various (hetero)aryl ketones are compatible in the reaction, affording the alkene product in good to excellent yields. Further applications in the late-stage olefination of some drugs, natural products, and fragrance-derived aryl ketones demonstrate the synthetic utility of this protocol. By employing ketone as both the directing group and the leaving group, 1,2-bifunctionalization is achieved via sequential ortho-C-H alkylation/ipso-Heck olefination.

Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21

Searching for novel antiobesity agents, a series of cannabinoid LH21 and of Rimonabant-fatty acid amide analogues have been prepared. Synthesis of pyrazoles 2a-2c was achieved by a two steps simple methodology via α,β-unsaturated ketones. Carboxamides 8a-8h were obtained in good yields from esters 7a-7c by a one-pot procedure which takes place under mild conditions. New compounds have been evaluated in vivo as anorectic agents. Some of them showed interesting properties reducing food intake in rats by a mechanism which does not involve the endocannabinoid system.

Recyclable gold nanoparticle catalyst for the aerobic alcohol oxidation and C-C bond forming reaction between primary alcohols and ketones under ambient conditions

A recyclable gold catalyst is synthesized from readily available reagents by immobilizing gold nanoparticles in aluminum oxyhydroxide support through a simple sol-gel method. The catalyst showed the high activity even at room temperature in the aerobic oxidation of various alcohols and in the coupling reaction between primary alcohols and ketones.