39652-34-1

Basic information

• Product Name: 3,5-Dichloro-4-methylbenzoic acid
• Synonyms: 3,5-Dichloro-4-methylbenzoic acid
• CAS NO: 39652-34-1
• Molecular Formula: C₈H₆Cl₂O₂
• Molecular Weight: 205.03804
• EINECS: 1592732-453-0
• Mol File: 39652-34-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 187-189 °C(Solv: hexane (110-54-3))
• Boiling Point: 330.9°Cat760mmHg
• Flash Point: 153.9°C
• Appearance: /
• Density: 1.442g/cm³
• Vapor Pressure: 6.44E-05mmHg at 25°C
• Refractive Index: 1.587
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 3.63±0.10(Predicted)
• CAS DataBase Reference: 3,5-Dichloro-4-methylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-4-methylbenzoic acid(39652-34-1)
• EPA Substance Registry System: 3,5-Dichloro-4-methylbenzoic acid(39652-34-1)

Safety Data

• Hazardous Substances Data: 39652-34-1(Hazardous Substances Data)

Usage

General Description

3,5-Dichloro-4-methylbenzoic acid is a chemical compound with the molecular formula C8H6Cl2O2. It is an aromatic compound with two chlorine atoms and a methyl group attached to a benzoic acid backbone. 3,5-Dichloro-4-methylbenzoic acid is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and it has also been studied for its potential as an anti-cancer agent. Additionally, 3,5-Dichloro-4-methylbenzoic acid has been used in the production of dyes and pigments, as well as in the synthesis of various organic compounds. It is important to handle this chemical with care, as it is considered potentially hazardous and may have harmful effects if not used properly.

InChI:InChI=1/C8H6Cl2O2/c1-4-6(9)2-5(8(11)12)3-7(4)10/h2-3H,1H3,(H,11,12)

Upstream product

• 99-94-5 p-Toluic acid 
• 122-00-9 para-methylacetophenone 
• 5162-82-3 3-chloro-4-methylbenzoic acid 
• 181871-69-2 3-chloro-4-methyl-5-nitro benzoic acid 
• 88541-40-6 1-(3,5-dichloro-4-methyl-phenyl)-ethanone 
• 6633-36-9 3,5-diamino-4-methylbenzoic acid 
• 64-19-7 acetic acid 
• 124-38-9 carbon dioxide 
• 177167-52-1 1,3-dichloro-5-iodo-2-methylbenzene 
• 118-69-4 2,6-dichlorotoluene 
• 3032-81-3 3,5-dichloroiodobenzene 

Downstream Products

• 859212-75-2 methyl 4-(bromomethyl)-3,5-dichlorobenzoate 
• 153203-78-2 4-bromomethyl-3,5-dichlorobenzoic acid 
• 156052-68-5 zoxamide 
• 1465326-89-9 methyl 3,5-dichloro-4-formylbenzoate 
• 203573-09-5 methyl-3,5-dichloro-4-methylbenzoate 
• 118-69-4 2,6-dichlorotoluene 
• 113485-46-4 3,5-dichloro-4-methylbenzoyl chloride 

Relevant articles and documents

Industrialized synthetic method for halogen benzoic acid derivative

The invention discloses an industrialized synthetic method for a halogen benzoic acid derivative. The formula (I) of the halogen benzoic acid derivative is shown in the description, wherein a plurality of Rs are alkyls of C1-C20, and a plurality of Xs are halogens; the industrialized synthetic method comprises the following steps that alkyl substituted benzoic acid and water are added into a reaction container, halogen simple substances are added, a heating reaction is performed, the reaction is complete, and post processing is performed to obtain the target product halogen benzoic acid derivative. According to the industrialized synthetic method for the halogen benzoic acid derivative, no solvent needs to be recycled, little consumption is consumed, little waste gas, water and industrialresidues are caused, and by-product haloid acid can be directly sold or used for producing other products; accordingly, the industrialized synthetic method for the halogen benzoic acid derivative is safe, environmentally friendly and low in cost, and therefore the wide industrial application prospect is achieved.

Proton mobility in 2-substituted 1,3-dichlorobenzenes: "ortho" or "meta" metalation?

Nine 1,3-dichlorobenzene congeners were selected as model compounds to assess the relative rates of proton abstraction from 4- and 5-positions ("ortho" vs. "meta" metalation). Using lithium 2,2,6,6-tetramethylpiperidide as the basic reagent, the chlorine-adjacent 4-position underwent metalation exclusively. In contrast, attack at the chlorine-remote 5-posi" tion became significant even in the case of moderately sized 2-substituents (such as dimethylamino or ethyl) when secbutyllithium was employed. The "ortho/para" (4-/5-) ratios ranged from 80:20 to 65:35. The more pronounced "meta-orienting" effect of silicon as opposed to carbon substituents can be attributed to dissimilarities in the n polarization of the aromatic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

N-acetonylbenzamides and their use as fungicides

Novel N-acetonylbenzamides and their use in controlling phytopathogenic fungi.