39652-34-1

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3,5-Dichloro-4-methylbenzoic acid is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its specific structural features make it a valuable component in the development of new drugs and agricultural products.
Used in Anti-Cancer Research:
3,5-Dichloro-4-methylbenzoic acid has been studied for its potential as an anti-cancer agent. Its chemical properties may contribute to the inhibition of cancer cell growth and the modulation of signaling pathways involved in tumor progression.
Used in Dye and Pigment Production:
3,5-Dichloro-4-methylbenzoic acid has also found applications in the production of dyes and pigments, where its chemical structure imparts specific color characteristics and properties to the final products.
Used in Organic Synthesis:
3,5-Dichloro-4-methylbenzoic acid is employed in the synthesis of various organic compounds, serving as a building block for the creation of more complex molecules with diverse applications.
It is crucial to handle 3,5-Dichloro-4-methylbenzoic acid with care due to its potentially hazardous nature, ensuring proper safety measures are in place to prevent harmful effects during its use.

InChI:InChI=1/C8H6Cl2O2/c1-4-6(9)2-5(8(11)12)3-7(4)10/h2-3H,1H3,(H,11,12)

Upstream product

• 64-19-7 acetic acid 
• 124-38-9 carbon dioxide 
• 118-69-4 2,6-dichlorotoluene 
• 177167-52-1 1,3-dichloro-5-iodo-2-methylbenzene 
• 5162-82-3 3-chloro-4-methylbenzoic acid 
• 99-94-5 p-Toluic acid 
• 122-00-9 para-methylacetophenone 
• 3032-81-3 3,5-dichloroiodobenzene 
• 181871-69-2 3-chloro-4-methyl-5-nitro benzoic acid 
• 88541-40-6 1-(3,5-dichloro-4-methyl-phenyl)-ethanone 
• 6633-36-9 3,5-diamino-4-methylbenzoic acid 

Downstream Products

• 859212-75-2 methyl 4-(bromomethyl)-3,5-dichlorobenzoate 
• 153203-78-2 4-bromomethyl-3,5-dichlorobenzoic acid 
• 156052-68-5 zoxamide 
• 1465326-89-9 methyl 3,5-dichloro-4-formylbenzoate 
• 203573-09-5 methyl-3,5-dichloro-4-methylbenzoate 
• 118-69-4 2,6-dichlorotoluene 
• 113485-46-4 3,5-dichloro-4-methylbenzoyl chloride 

Relevant academic research and scientific papers

Industrialized synthetic method for halogen benzoic acid derivative

The invention discloses an industrialized synthetic method for a halogen benzoic acid derivative. The formula (I) of the halogen benzoic acid derivative is shown in the description, wherein a plurality of Rs are alkyls of C1-C20, and a plurality of Xs are halogens; the industrialized synthetic method comprises the following steps that alkyl substituted benzoic acid and water are added into a reaction container, halogen simple substances are added, a heating reaction is performed, the reaction is complete, and post processing is performed to obtain the target product halogen benzoic acid derivative. According to the industrialized synthetic method for the halogen benzoic acid derivative, no solvent needs to be recycled, little consumption is consumed, little waste gas, water and industrialresidues are caused, and by-product haloid acid can be directly sold or used for producing other products; accordingly, the industrialized synthetic method for the halogen benzoic acid derivative is safe, environmentally friendly and low in cost, and therefore the wide industrial application prospect is achieved.

Method for synthesizing 2,6-dichloro p-toluic acid

Provided is a method for preparing 2,6-dichloro p-toluic acid. According to the method, p-toluylic acid is adopted as an initial raw material, dichloroacetic acid is adopted as a solvent, and in the presence of tungstate and hydrochloric acid, hydrogen pe

Proton mobility in 2-substituted 1,3-dichlorobenzenes: "ortho" or "meta" metalation?

Nine 1,3-dichlorobenzene congeners were selected as model compounds to assess the relative rates of proton abstraction from 4- and 5-positions ("ortho" vs. "meta" metalation). Using lithium 2,2,6,6-tetramethylpiperidide as the basic reagent, the chlorine-adjacent 4-position underwent metalation exclusively. In contrast, attack at the chlorine-remote 5-posi" tion became significant even in the case of moderately sized 2-substituents (such as dimethylamino or ethyl) when secbutyllithium was employed. The "ortho/para" (4-/5-) ratios ranged from 80:20 to 65:35. The more pronounced "meta-orienting" effect of silicon as opposed to carbon substituents can be attributed to dissimilarities in the n polarization of the aromatic ring. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.

Oxidative chlorination, desulphonation, or decarboxylation to synthesize pharmaceutical intermediates: 2,6-Dichlorotoluene, 2,6-dichloroaniline, and 2,6-dichlorophenol

An alternative manufacturing process scheme was developed for 2,6-dichlorotoluene, 2,6-dichloroaniline, and 2,6-dichlorophenol, involving oxidative chlorination after protection of the starting material in the para position followed by deprotection involving desulphonation or decarboxylation. Oxidative chlorination of 4-methylbenzenesulphonic acid, 4-methylbenzoic acid, 4-aminobenzoic acid, and 4-hydroxybenzoic acid by using HCl-H2O2, and their subsequent desulphonation or decarboxylation, gave a 60-75% yield of the desired product.

N-acetonylbenzamides and their use as fungicides

Novel N-acetonylbenzamides and their use in controlling phytopathogenic fungi.

N-acetonylbenzamides and their use as fungicides

Certain N-acetonylbenzamides exhibit low phytotoxicity and are useful for control of a wide range of fungi, including phytopathogenic fungi of the classes Oomycetes, Ascomycetes, Deuteromycetes and Basidiomycetes.