40617-52-5

Upstream product

• 6245-04-1 3,5-dimethylsalicylic acid 
• 65448-72-8 2-hydroxy-3-(hydroxymethyl)-5-methylbenzaldehyde 
• 197906-32-4 2-methoxy-5-methylbenzene-1,3-dicarboxylic acid 
• 3453-83-6 mesitylene sulfonic acid 
• 91-04-3 2,6-bis(hydroxymethyl)-4-methylphenol 
• 106-44-5 p-cresol 
• 6327-85-1 2,6-bis(hydroxymethyl)-4-methyl-anisole 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 
• 192819-68-4 3-chloromethyl-5-methylsalicylaldehyde 
• 7310-95-4 2-Hydroxy-5-methylisophthalaldehyde 

Downstream Products

• 129117-85-7 dimethyl 2-hydroxy-5-methylbenzene-1,3-dicarboxylate 
• 201416-10-6 dimethyl 2-methoxy-5-methylisophthalate 
• 1612753-17-9 tri-tert-butyl 10-(2-((4-methoxy-3,5-bis(methylcarbamoyl)benzyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate 
• 1612753-16-8 5-(aminomethyl)-2-methoxy-N¹,N³-dimethylisophthalamide 
• 1630981-41-7 5-(aminomethyl)-2-methoxy-N¹,N³-dimethylisophthalamide hydrochloride 
• 1612753-15-7 5-((hydroxyimino)methyl)-2-methoxy-N¹,N³-dimethylisophthalamide 
• 1612753-14-6 5-formyl-2-methoxy-N¹,N³-dimethylisophthalamide 
• 1612753-23-7 hexaethyl-2,2',2''-((2,2',2''-(10-(2-((4-methoxy-3,5-bis(methylcarbamoyl)benzyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)tris(acetyl))tris(azanediyl))tripentanedioate 
• 1612753-13-5 2-methoxy-N¹,N³,5-trimethylisophthalamide 
• 1612753-22-6 triethyl-2,2',2''-((2,2',2''-(10-(2-((4-methoxy-3,5-bis(methylcarbamoyl)benzyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)tris(acetyl))tris(azanediyl))tripropanoate 
• 1612753-21-5 2-methoxy-N¹,N³-dimethyl-5-((2-(4,7,10-tris(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetamido)methyl)isophthalamide 
• 1612753-20-4 2-methoxy-N¹,N³-dimethyl-5-((2-(4,7,10-tris(2-(hexylamino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetamido)methyl)isophthalamide 
• 1612753-19-1 2-methoxy-N¹,N³-dimethyl-5-((2-(4,7,10-tris(2-(benzylamino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecan-1-yl)acetamido)methyl)isophthalamide 
• 1612753-26-0 2,2',2''-(10-(2-((4-hydroxy-3,5-bis(methylcarbamoyl)benzyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid 

Relevant academic research and scientific papers

Oxidative DNA Cleavage, Formation of μ-1,1-Hydroperoxo Species, and Cytotoxicity of Dicopper(II) Complex Supported by a p-Cresol-Derived Amide-Tether Ligand

Metal complexes to promote oxidative DNA cleavage by H2O2 are desirable as anticancer drugs. A dicopper(II) complex of known p-cresol-derived methylene-tether ligand Hbcc [Cu2(bcc)]3+ did not promote DNA cleavag

DINUCLEATING LIGAND OR DINUCLEAR METAL COMPLEX

To provide a dinuclear metal complex that can be synthesized simply and easily and has a proper anticancer action.SOLUTION: The present disclosure provides a dinucleating ligand represented by the following formula (I) and a dinuclear metal complex thereof (where each X may be the same or different to represent H, Cl, OMe, or, Me, Y is H, a phenyl group, a substituted carbamoyl group or the like).SELECTED DRAWING: None

DINUCLEATING LIGAND OR DINUCLEAR METAL COMPLEX

To provide a dinuclear metal complex that can be synthesized simply and easily and has a proper anticancer action.SOLUTION: The present disclosure provides a dinucleating ligand represented by the following formula (I) and a dinuclear metal complex thereof (where X is H or a substituted carbamoyl group, R1, R2, R3, and R4 independently represent H or a C1-8 linear or branched alkyl group).SELECTED DRAWING: None

BINUCLEATING LIGAND OR BINUCLEAR METAL COMPLEX

PROBLEM TO BE SOLVED: To provide a binuclear metal complex that can be easily synthesized and has a proper anticancer action. SOLUTION: The present invention provides a binuclear metal complex represented by the following chemical formula (IV). SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2018,JPOandINPIT

DIAMINE COMPOUND, AND HEAT-RESISTANT RESIN OR HEAT-RESISTANT RESIN PRECURSOR USING SAME

Provided are a photosensitive resin composition which has excellent pattern processabilities (high sensitivity and high resolution) and is excellent in chemical resistance and thermal resistance after thermally treated; a heat-resistant resin or heat-resi

Effect of lanthanide complex structure on cell viability and association

A systematic study of the effect of hydrophobicity and charge on the cell viability and cell association of lanthanide metal complexes is presented. The terbium luminescent probes feature a macrocyclic polyaminocarboxylate ligand (DOTA) in which the hydrophobicity of the antenna and that of the carboxyamide pendant arms are independently varied. Three sensitizing antennas were investigated in terms of their function in vitro: 2-methoxyisophthalamide (IAM(OMe)), 2-hydroxyisophthalamide (IAM), and 6-methylphenanthridine (Phen). Of these complexes, Tb-DOTA-IAM exhibited the highest quantum yield, although the higher cell viability and more facile synthesis of the structurally related Tb-DOTA-IAM(OMe) platform renders it more attractive. Further modification of this latter core structure with carboxyamide arms featuring hydrophobic benzyl, hexyl, and trifluoro groups as well as hydrophilic amino acid based moieties generated a family of complexes that exhibit high cell viability (ED 50 > 300 μM) regardless of the lipophilicity or the overall complex charge. Only the hexyl-substituted complex reduced cell viability to 60% in the presence of 100 μM complex. Additionally, cellular association was investigated by ICP-MS and fluorescence microscopy. Surprisingly, the hydrophobic moieties did not increase cell association in comparison to the hydrophilic amino acid derivatives. It is thus postulated that the hydrophilic nature of the 2-methoxyisophthalamide antenna (IAM(OMe)) disfavors the cellular association of these complexes. As such, responsive luminescent probes based on this scaffold would be appropriate for the detection of extracellular species.

A mononuclear copper(ii) complex immobilized in mesoporous silica: An efficient heterogeneous catalyst for the aerobic oxidation of benzylic alcohols

The diamide ligand 2,6-bis[(N-phenyl)amido]-4-methylphenol (HL) has been used to synthesize a mononuclear copper(ii) complex, [CuL2(DMF) 2] (1). The X-ray crystal structure of this complex reveals that the copper(ii) center is coordi