40626-45-7

Usage

Appearance

White to light yellow crystalline solid

Solubility

Insoluble in water, soluble in most organic solvents

Odor

Strong and characteristic

Stability

Stable and non-reactive

Handling

Hazardous substance, can cause irritation to skin, eyes, and respiratory system

Safety Precautions

Work in well-ventilated area and wear appropriate protective equipment.

Upstream product

• 140-29-4 phenylacetonitrile 
• 100-47-0 benzonitrile 
• 7791-25-5 sulfuryl dichloride 
• 56630-21-8 C₈H₅Cl₂NS 
• 613-90-1 benzoyl cyanide 

Downstream Products

• 60388-86-5 2-Imino-3,3-dichloro-3-phenylpropionitril 
• 613-90-1 benzoyl cyanide 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 60388-88-7 2-Acetylamino-3-chlor-3-phenylacrylnitril 
• 60388-89-8 N-(1-cyano-2-phenylethenyl) acetamide 
• 28798-97-2 2,2,4-trichloro-6-(dichloro-phenyl-methyl)-2λ⁵-[1,3,2]diazaphosphinine-5-carbonitrile 
• 36251-43-1 2,4-dichloro-6-(dichloro-phenyl-methyl)-2-oxo-1(3),2-dihydro-2λ⁵-[1,3,2]diazaphosphinine-5-carbonitrile 
• 650-93-1 2,2-difluoro-2-(3-nitrophenyl)acetic acid 
• 339-30-0 2,2-difluoro-N-2-diphenylacetamide 
• 2248-46-6 ethyl 2,2-difluoro-2-phenylacetate 
• 402-03-9 (3-amino-phenyl)-difluoro-acetic acid 
• 383-19-7 2,2-difluoro-2-phenylacetamide 
• 312-24-3 difluoro-phenyl-acetyl chloride 
• 360-03-2 2,2-Difluoro-2-phenylacetic acid 

Relevant academic research and scientific papers

Novel synthesis method for oxophenylacetate

The invention discloses a novel synthesis method for oxophenylacetate and belongs to the technical field of synthesis. The novel synthesis method comprises the steps: firstly, reacting benzonitrile and a halogenation reagent at 20-35 DEG C to obtain dihalogenated phenylacetonitrile; then, adding a mixed solution of acid and water into dihalogenated phenylacetonitrile at 35-55 DEG C, and carrying out a reaction at 50-60 DEG C for 2-8 h, wherein the molar ratio of a product I to the water to the acid is 1:(1-10):(1-10); and finally, adding alcohol into the reaction solution in the former step at50-60 DEG C, then, carrying out stirring, controlling the temperature at 60-70 DEG C, carrying out a constant-temperature reaction for 1-4 h, and carrying out cooling and extraction to obtain a target product. The reaction raw materials adopted in the method are wide in source and low in price, the operation process is simple, and the yield of the product is high.

Oxidation using Phase Transfer Catalyst - A Mechanistic Study

Oxidation of benzyl alcohol and benzyl cyanide by sodium hypochlorite under phase transfer conditions involves initial chlorination at the benzylic carbon.Since no reaction takes place in the absence of a phase transfer catalyst, it clearly indicates involvement of an ionic species in the organic phase.