40738-26-9Relevant articles and documents
Lipase-catalyzed two-step esterification for solvent-free production of mixed lauric acid esters with antibacterial and antioxidative activities
Yu, Hyunjong,Byun, Yerim,Chang, Pahn-Shick
, (2021/08/01)
Mixed lauric acid esters (MLE) with antibacterial and antioxidative activities were produced through lipase-catalyzed two-step esterification in solvent-free system without purification. In the first reaction, erythorbyl laurate was synthesized for 72 h. Successive reaction for 6 h at molar ratio of 1.0 (lauric acid to glycerol) produced MLE containing erythorbyl laurate and glyceryl laurate with small amounts of residual substrates, by converting 99.52% of lauric acid. MLE addition (0.5–2.0%, w/w) to Tween 20-stabilized emulsions decreased droplet size, polydispersity index, and zeta-potential, possibly enhancing the emulsion stability. In the emulsions, MLE at 0.5 and 2.0% (w/w) caused 4.4–4.6 and 5.9–6.1 log reductions of Gram-positive (Staphylococcus aureus, Listeria monocytogenes) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), respectively, within 12 h. Lipid hydroperoxide concentrations decreased to 50.8–98.3% in the presence of 0.5–2.0% (w/w) MLE. These findings support a novel approach without needing purification to produce multi-functional food additives for emulsion foods.
Preparation method of glycerol monolaurate
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Paragraph 0052; 0057-0112, (2021/08/07)
The invention provides a preparation method of glycerol monolaurate, and belongs to the field of organic synthesis. According to the method, lauric acid and glycerol are used as raw materials, the glycerol esterification reaction of long-chain fatty acid lauric acid is catalyzed through an acid catalyst, and an eutectic solvent is used as a solvent, so that the activation energy of the esterification reaction can be reduced, the esterification reaction can be carried out at a relatively low temperature, and meanwhile, the eutectic solvent is easily separated from and recycled from a product; and on one hand, hydroxyl on a glycerol structure can be protected, esterification reaction is promoted to directionally and selectively generate glycerol monolaurate, and generation of a byproduct diester is inhibited, so that the selectivity, the yield and the purity of the product glycerol monolaurate are improved. The result of the embodiment shows that the glycerol monolaurate can be prepared at the low temperature of 120-160 DEG C by utilizing the method provided by the invention, the product selectivity is 87.1%, the yield is 76.4%, and the purity is 89.4%.
High-selectivity synthesis method of long-chain fatty acid monoglyceride
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Paragraph 0023; 0026, (2019/02/27)
The invention belongs to the field of fatty acid and synthetic fatty acid glycerides and relates to a high-selectivity synthesis method of long-chain fatty acid monoglyceride, in particular to a high-selectivity synthesis method of long-chain fatty acid and synthetic fatty acid glycerides. The method comprises the steps that tetraethyl silicate and glycerin are subjected to alcoholysis reaction, and part of glycerin is esterified to generate glyceryl silicate; then the glyceryl silicate is subjected to esterification reaction with fatty acid to generate fatty acid glyceride; finally the high activity (instability) of silicate ester is utilized to achieve hydrolysis under mild conditions to synthesize the synthetic fatty acid glyceride at high selectivity. A by-product is safe and harmlessSiO2. Accordingly, the product with high monoglyceride content is obtained by using a simple process under mild conditions.
