14213-16-2

Basic information

• Product Name: 5-methyl-1-phenyl-1H-tetrazole
• Synonyms: 1H-tetrazole, 5-methyl-1-phenyl-; 5-Methyl-1-phenyl-1H-tetrazole
• CAS NO: 14213-16-2
• Molecular Formula: C₈H₈N₄
• Molecular Weight: 160.1759
• Mol File: 14213-16-2.mol
• Article Data: 13

Chemical Properties

• Refractive Index: 1.657
• CAS DataBase Reference: 5-methyl-1-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-phenyl-1H-tetrazole(14213-16-2)
• EPA Substance Registry System: 5-methyl-1-phenyl-1H-tetrazole(14213-16-2)

Safety Data

• Hazardous Substances Data: 14213-16-2(Hazardous Substances Data)

Upstream product

• 26060-56-0 (1-phenylethylidene)(benzoyloxy)amine 
• 621-09-0 N,N'-diphenylacetamidine 
• 3148-73-0 Diacetylhydrazin 
• 100-34-5 benzene diazonium chloride 
• 2208-07-3 ethyl acetimidate hydrochloride 
• 62-53-3 aniline 
• 98-86-2 acetophenone 
• 75-05-8 acetonitrile 
• 10341-75-0 (E)-1-phenylethanone oxime 
• 536-74-3 phenylacetylene 
• 16717-64-9 1-azidostyrene 
• 107269-80-7 (E)-1-Phenyl-5-tetrazolcarbaldehyd-tosylhydrazon 
• 107269-89-6 (Z)-1-Phenyl-5-tetrazolcarbaldehyd-tosylhydrazon 
• 98-88-4 benzoyl chloride 

Downstream Products

• 19813-37-7 (1-phenyl-1H-tetrazol-5-yl)-acetic acid 
• 114282-55-2 1-ethyl-5-methyl-4-phenyl-tetrazolium; iodide 
• 100518-01-2 (1-phenyl-1H-tetrazol-5-yl)-pyruvic acid ethyl ester 
• 4172-91-2 N-((methylimino)methylene)aniline 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 101-01-9 N,N',N''-triphenylguanidine 
• 10493-81-9 1,2-Dimethyl-3-phenylguanidin 
• 62-53-3 aniline 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 96746-54-2 1-benzyl-5-phenyl-1H-tetrazole 
• 56805-03-9 N-ethyl<²H2>aniline 
• 19597-69-4 lithium azide 
• 40746-64-3 5-methyl-1-(3-nitrophenyl)tetrazole 
• 40746-65-4 5-methyl-1-(4-nitrophenyl)-1H-tetrazole 

Relevant articles and documents

5-Benzyl-1H-tetrazols from the reaction of 1-aryl-5-methyl-1H-tetrazoles with 1,2-dehydrobenzene

A series of 1-aryl-5-benzyl-1H-tetrazoles has been obtained during the reaction of 1-aryl-5-methyl-1H-tetrazoles with 1,2-dehydrobenzene. The mechanism of product formation was investigated.

Reductive Fragmentation of Tetrazoles: Mechanistic Insights and Applications toward the Stereocontrolled Synthesis of 2,6-Polysubstituted Morpholines

A new methodology to synthesize 2,6-di-, and 2,2′,6-trisubstituted morpholines via the reduction of oxabicyclic tetrazoles under mild conditions is described. The reaction proved successful for a wide range of tetrazoles, including sterically encumbered ones harboring gem-substituents on tertiary carbon centers. The mechanism for the decades-old reduction of tetrazoles to secondary amines is elucidated.

An efficient synthesis of nitrile, tetrazole and urea from carbonyl compounds

An efficient conversion of carbonyl compounds (aldehydes and ketones) to nitrile, tetrazole, and urea was developed with the use of a POCl3 and sodium azide mixture using a convergent and microwave method. This is the first report on the direct conversion of ketone to urea. The synthesized compounds were characterized by 1H NMR, 13C NMR, mass and IR spectroscopies and were found to be in agreement with reported compounds.

Efficient synthesis of 1,5-disubstituted tetrazoles

A general method for the synthesis of 1,5-disubstituted tetrazoles from imidoylbenzotriazoles that involves mild reaction conditions and short reaction times. Georg Thieme Verlag Stuttgart.