41019-23-2

Basic information

• Product Name: benzoic acid-(2-acetyl-4-chloro-anilide)
• Synonyms: benzoic acid-(2-acetyl-4-chloro-anilide)
• CAS NO: 41019-23-2
• Molecular Weight: 273.719
• Mol File: 41019-23-2.mol

Chemical Properties

• CAS DataBase Reference: benzoic acid-(2-acetyl-4-chloro-anilide)(CAS DataBase Reference)
• NIST Chemistry Reference: benzoic acid-(2-acetyl-4-chloro-anilide)(41019-23-2)
• EPA Substance Registry System: benzoic acid-(2-acetyl-4-chloro-anilide)(41019-23-2)

Safety Data

• Hazardous Substances Data: 41019-23-2(Hazardous Substances Data)

Upstream product

• 1685-19-4 2-amino-5-chloroacetophenone 
• 736145-09-8 benzoic acid-(2-acetyl-4-amino-anilide) 
• 41018-94-4 5-chloro-3-methyl-2-phenyl-1H-indole 
• 5234-26-4 N-(2-acetylphenyl)acetamide 
• 41019-20-9 N-(2-acetyl-4-nitro-phenyl)-acetamide 
• 1678-04-2 benzoic acid-(2-acetyl-4-nitro-anilide) 
• 32580-41-9 1-(2-amino-5-nitro-phenyl)ethanone 

Downstream Products

• 112182-50-0 6-chloro-2-phenylquinolin-4(1H)-one 

Relevant articles and documents

Oxidative Cleavage of Indoles Mediated by Urea Hydrogen Peroxide or H2O2 in Polar Solvents

The oxidative cleavage of indoles (Witkop oxidation) involving the use of H2O2 or urea hydrogen peroxide in combination with a polar solvent has been described. Among these solvents, 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) stands out as the one affording the corresponding 2-ketoacetanilides generally in higher yields The protocol described has also enabled the oxidation of different pyrroles and furans derivatives. Furthermore, the procedure was implemented in a larger-scale and HFIP was distilled from the reaction mixture and reused (up to 4 cycles) without a significant detriment in the reaction outcome, which remarks its sustainability and applicability. (Figure presented.).