410544-56-8 Usage
Uses
Used in Pharmaceutical Research and Development:
1,6-Naphthyridine-7-carboxamide, 5-bromo-N-[(4-fluorophenyl)methyl]-8-hydroxyis used as an informer compound in the Aryl Halide Chemistry Informer Library for pharmaceutical research and development. Its application is to facilitate the comparison and analysis of a new reaction's successes and shortcomings among different methods and various research teams. This helps chemists to optimize and develop more efficient and effective chemical reactions for drug synthesis.
Used in Method Development:
1,6-Naphthyridine-7-carboxamide, 5-bromo-N-[(4-fluorophenyl)methyl]-8-hydroxyis also used as a tool to facilitate deeper method development for performance or utility in the pharmaceutical industry. By studying the behavior of 1,6-Naphthyridine-7-carboxamide,
5-bromo-N-[(4-fluorophenyl)methyl]-8-hydroxy- in different reactions, researchers can gain insights into the factors that influence reaction outcomes and use this knowledge to improve the overall efficiency and effectiveness of drug synthesis processes.
Check Digit Verification of cas no
The CAS Registry Mumber 410544-56-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,1,0,5,4 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 410544-56:
(8*4)+(7*1)+(6*0)+(5*5)+(4*4)+(3*4)+(2*5)+(1*6)=108
108 % 10 = 8
So 410544-56-8 is a valid CAS Registry Number.
410544-56-8Relevant academic research and scientific papers
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties
Zeng, Li-Fan,Wang, Yong,Kazemi, Roza,Xu, Shili,Xu, Zhong-Liang,Sanchez, Tino W.,Yang, Liu-Meng,Debnath, Bikash,Odde, Srinivas,Xie, Hua,Zheng, Yong-Tang,Ding, Jian,Neamati, Nouri,Long, Ya-Qiu
, p. 9492 - 9509 (2013/01/16)
Among a large number of HIV-1 integrase (IN) inhibitors, the 8-hydroxy-[1,6]naphthyridines (i.e., L-870,810) were one of the promising class of antiretroviral drugs developed by Merck Laboratories. In spite of its remarkable potency and efficacy, unfortun
Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors
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, (2008/06/13)
Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the
