412908-67-9

Upstream product

• 92817-88-4 (2S)-3-{[tert-butyl(diphenyl)silyl]oxy}-2-methylpropanal 
• 917871-11-5 (R)-(E)-(+)-5-(tert-butyldiphenylsilyloxy)-4-methyl-2-penten-1-ol 
• 1035677-71-4 ((2S,3S)-3-((S)-1-(tert-butyldiphenylsilyloxy)propan-2-yl)oxiran-2-yl)methanol 
• 95514-04-8 (R)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-03-7 (S)-3-(tert-butyl-diphenyl-silanyloxy)-2-methyl-propionic acid methyl ester 

Downstream Products

• 158497-90-6 tert-Butyl-[(2S,3R)-3-(4-methoxy-benzyloxy)-2-methyl-pent-4-enyloxy]-diphenyl-silane 
• 412908-78-2 (3R,4S)-5-(tert-Butyl-diphenyl-silanyloxy)-3-(4-methoxy-benzyloxy)-4-methyl-pentan-1-ol 
• 158497-91-7 (2S,3R)-3-(4-Methoxy-benzyloxy)-5-[(4-methoxy-phenyl)-diphenyl-methoxy]-2-methyl-pentan-1-ol 
• 259656-95-6 (3R,4S)-3-(4-methoxybenzyloxy)-4-methyl-5-hexen-1-ol 
• 412909-38-7 (3R,4S)-3-(4-methoxybenzyloxy)-4-methylhex-5-enoic acid 
• 412909-37-6 C₃₅H₃₈O₄ 
• 412908-65-7 (3R,4S)-3-(4-Methoxy-benzyloxy)-4-methyl-hex-5-enoic acid (S)-1-[(R)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-allyl ester 
• 603994-09-8 (2R,3R)-3-methoxy-5-(4'-methoxybenzyloxy)-2-methylpentanal 
• 301230-10-4 (3R,4S)-5-(tert-butyldiphenylsilyloxy)-3-methoxy-4-methylpentan-1-ol 

Relevant academic research and scientific papers

Approaches towards the total synthesis of carolacton: Synthesis of C1-C16 fragment

Abstract A stereoselective synthesis of the C1-C16 segment of biofilm inhibitor carolacton has been achieved. The synthetic strategy involves Sharpless asymmetric epoxidation, Roush crotylation, Steglich esterification, RCM reaction and selective reduction of a disubstituted olefin in the presence of a trisubstituted olefin using in situ generated diimide.

Total synthesis of octalactin A via ring-closing metathesis reaction

A new total synthesis of the novel lactone natural product octalactin A is described. The key step involves the facile construction of the eight-membered lactone core via ring-closing metathesis (RCM). This oxocene was elaborated to give the powerful anti