15978-93-5Relevant articles and documents
A method for the treatment of tumor cell proliferative diseases of platinum (II) compound
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Paragraph 0191; 0201; 0202; 0203, (2018/01/11)
Disclosed are a platinum compound with the leaving group malonic derivative "2" position substituent containing a primary amino, a secondary amino, a tertiary amino, and a quaternary amino, as well as pharmaceutically acceptable salt, preparation method thereof, and pharmaceutical composition containing the compound. Also disclosed are uses of the compound for treating cell proliferative diseases, particularly cancers. The platinum compound of the present invention has the high water solubility and the low toxicity.
METAL COMPLEX AND ANTICANCER AGENT CONTAINING THE SAME
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Paragraph 0083, (2017/02/23)
PROBLEM TO BE SOLVED: To provide a platinum complex more excellent in anticancer activity than the coexisting platinum anticancer such as cisplatin and oxaliplatin, and also reduced in side-effects. SOLUTION: Provided is a platinum complex represented by formula (1) as a myo-inositol-1,2,3,4,5,6-hexakisphosphate derivative, and also provided is a platinum complex such as a (1,10-phenanthroline)(N-9-anthranilic methyl-1, 4-butane diamine) platinum [m and n respectively independently denote 1 or 2 and m+n denotes 3]. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
PLATINUM COMPOUND HAVING AMINO OR ALKYLAMINO-CONTAINING SUCCINIC ACID DERIVATIVES AS LEAVING GROUP, PREPARTION METHOD THEREOF, AND USE THEREOF
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Paragraph 0172; 0173, (2014/12/09)
Disclosed are a category of platinum compounds having amino- or alkylamino-containing succinato derivatives as leaving group, or pharmaceutically acceptable salts thereof, preparation method thereof, and medicinal compositions containing the compounds. Also disclosed is a use of the compounds in treating cell proliferative diseases, especially cancers. The platinum compounds of the present invention have high water solubility and small toxic side effect.
