4173-74-4

Basic information

• Product Name: 3-Methyl-4-acetyl-1-phenyl-1H-pyrazole-5(4H)-one
• Synonyms: 1-Phenyl-3-methyl-4-acetyl-1H-pyrazole-5(4H)-one;3-Methyl-4-acetyl-1-phenyl-1H-pyrazole-5(4H)-one;4-Acetyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one;4-Acetyl-3-methyl-1-phenyl-2-pyrazolin-5-one
• CAS NO: 4173-74-4
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.24
• Mol File: 4173-74-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: 66-67 °C(Solv: water (7732-18-5))
• Boiling Point: 399.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.22±0.1 g/cm3(Predicted)
• PKA: 3.86±0.70(Predicted)
• CAS DataBase Reference: 3-Methyl-4-acetyl-1-phenyl-1H-pyrazole-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-4-acetyl-1-phenyl-1H-pyrazole-5(4H)-one(4173-74-4)
• EPA Substance Registry System: 3-Methyl-4-acetyl-1-phenyl-1H-pyrazole-5(4H)-one(4173-74-4)

Safety Data

• Hazardous Substances Data: 4173-74-4(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 79-03-8 propionyl chloride 
• 89-25-8 edaravone 
• 75-36-5 acetyl chloride 

Downstream Products

• 68347-44-4 5-methyl-4-(3-morpholin-4-yl-propionyl)-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 66479-49-0 4-(3-furan-2-yl-acryloyl)-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 67867-80-5 4-(1-benzothiazol-2-ylamino-ethylidene)-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 30020-73-6 4-(3-benzo[1,3]dioxol-5-yl-acryloyl)-5-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 64360-25-4 3-methyl-1,6-diphenylpyrano[2,3-c]pyrazol-4(1H)-one 
• 64360-24-3 3,6-dimethyl-1-phenylpyrano[2,3-c]pyrazole-4(1H)-one 
• 64360-21-0 3-methyl-4-oxo-1-phenyl-1,4-dihydro-pyrano[2,3-c]pyrazole-6-carboxylic acid ethyl ester 

Relevant articles and documents

A highly sensitive and selective schiff base fluorescent chemodosimeter for aluminum(III)

A fluorescent probe for Al3+, 4-(1'-phenyl-3'-methyl-5'- hydroxypyrazole)-1-acetone-(2'-hydroxybenzoyl) hydrazone (L), was prepared through a simple synthetic route. The fluorescent probe can detect Al 3+ ions sensitively, in ethanol

Two Schiff-base fluorescent sensors for selective sensing of aluminum (III): Experimental and computational studies

Two Schiff-base fluorescent sensors have been synthesized, which both can act as fluorescent probes for Al3+, upon addition of Al3+, they exhibit a large fluorescence enhancement which might be attributed to the formation of 1:1 liga

Synthesis and luminescence properties of pyrazolone derivatives and their terbium complexes

Seven novel pyrazolone derivatives were synthesized and characterized by 1H NMR and 13C NMR spectra, mass spectra, infrared spectra and elemental analysis. Their terbium complexes were prepared and characterized by elemental analysis, EDTA titrimetric analysis, UV/vis spectra, infrared spectra and molar conductivity, as well as thermal analysis. The fluorescence properties and fluorescence quantum yields of the complexes were investigated at room temperature. The results indicated that pyrazolone derivatives had good energy-transfer efficiency for the terbium ion. All the terbium complexes emitted green fluorescence characteristic of terbium ions, possessed strong fluorescence intensity, and showed relatively high fluorescence quantum yields. Cyclic voltammograms of the terbium complexes were studied and the highest occupied molecular orbital (HOMO) and lowest occupied molecular orbital (LUMO) energy levels of these complexes were estimated.