4194-36-9Relevant academic research and scientific papers
Domino aryne precursor: Efficient construction of 2,4-disubstituted benzothiazoles
Shi, Jiarong,Qiu, Dachuan,Wang, Juan,Xu, Hai,Li, Yang
supporting information, p. 5670 - 5673 (2015/05/20)
An aryne precursor with a potential to perform domino aryne chemistry was proposed and synthesized. The reaction of this reagent with benzothioamide derivatives could afford 2,4-disubstituted benzothiazole with sequential incorporation of C-S, C-N, and C-C bonds on the consecutive three positions of the aryne precursor.
The Triethylamine Catalyzed Reaction of N,N-Disubstituted Thioamide-Bromine Adducts With Unsubstituted Thiobenzamide
Corsaro, Antonino,Compagnini, Anna,Perrini, Giancarlo,Purrello, Giovanni
, p. 897 - 900 (2007/10/02)
The reaction of N,N-disubstituted thioamide-bromine adducts with unsubstituted thioamide, followed by treatment with triethylamine, affords novel N'-thiobenzoylamidines along with smaller amounts of secondary products.A mechanism is proposed for the formation of the amidines.The results give an insight into the initial steps of the mechanism by which thioamides are converted into 1,2,4-thiadiazoles.
Heterocycles from N-Benzoylthioamides and Dinucleophilic Reagents
Whitfield, Lawrence L.,Papadopoulos, Eleftherios P.
, p. 1197 - 1201 (2007/10/02)
N-Benzoylthioamides (I) react with hydrazines and hydroxylamine to form 1H-1,2,4-triazoles and 1,2,4-oxazoles, respectively.A similar treatment of the S-methyl derivatives of 1 with amidines leads to 1,3,5-triazines.Ethyl N-benzoylthiocarbamate undergoes analogous reactions to yield the corresponding ethoxyheterocycles.
