42164-54-5Relevant articles and documents
Synthesis of imidazolidin-2-ones employing dialkyl carbonates as an ecofriendly carbonylation source
Badru, Rahul,Singh, Baldev
, p. 38978 - 38985 (2014/11/07)
A new approach to the synthesis of imidazolidin-2-ones by carbonylation of vicinal diamines with dialkyl carbonates using Pb(NO3)2 and Cu(ii) salts as catalysts has been described in the present protocol. A comparative study using Cu(ii) salts and Pb(NO3)2 as catalysts has suggested Cu(NO3)2 and CuCl 2·2H2O salts to be as promising as Pb(NO 3)2 and can replace the latter in the carbonylation reactions employing dialkyl carbonates. the Partner Organisations 2014.
NOVEL COMPOUNDS
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Page/Page column 23, (2010/02/07)
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as glucocorticoid receptor modulators. The compounds of the instant invention are ligands for glucocorticoid receptors and as such may be useful for treatment or prevention of a variety of conditions related to glucocorticoid functioning including rheumatoid arthritis, osteoarthritis, allery, asthma, pneumonia, dermatitis, eczema, psoriasis, lupus, colitis, inflammatory bowel disease, multiple sclerosis, congenital neutropenia, Wegener's granulomatosis, Addison's Disease, Crohn's disease Cushing Syndrome, or as immunosuppressants in organ transplantation.
A Convenient Synthesis of 1,2,5-Trisubstituted 4,5-Dihydroimidazoles and 1,3-Diazaspiroalk-2-enes from N-Alkylideneanilines
Naim, S. Shawkat,Sharma, Satyavan
, p. 664 - 666 (2007/10/02)
A convenient synthesis of 5-aryl-4,5-dihydro-2-methoxycarbonylamino-1-phenylimidazoles 5a-d and 2-methoxycarbonylamino-1-phenyl-1,3-diazaspiroalk-2-enes 5e,f has been reported from N-alkylideneanilines 1a-f via cyclization of the corresponding 1,2