42164-54-5

Usage

Uses

Used in Analytical Chemistry:
N1,1-Diphenyl-1,2-ethanediamine is used as a reagent for detecting the presence of free chlorine in water samples. Its reaction with free chlorine results in a color change to pink, which can be quantitatively measured to ascertain the concentration of free chlorine, ensuring water quality and safety.
Used in Swimming Pool Water Testing:
In the swimming pool industry, N1,1-Diphenyl-1,2-ethanediamine is utilized in water testing kits to maintain appropriate chlorine levels for sanitation. The color change it induces upon reaction with chlorine serves as an indicator of whether the pool water is within the recommended range for effective disinfection.
Used in Medicinal Chemistry Research:
N1,1-Diphenyl-1,2-ethanediamine is studied for its potential as an antioxidant, with the capacity to scavenge free radicals. This property makes it a subject of interest in medicinal chemistry, where it could potentially be developed into a therapeutic agent for various health applications related to oxidative stress and related conditions.

InChI:InChI=1/C14H16N2/c15-11-14(12-7-3-1-4-8-12)16-13-9-5-2-6-10-13/h1-10,14,16H,11,15H2

Upstream product

• 4553-59-7 2-anilino-2-phenylacetonitrile 
• 21080-09-1 NSC 4573 
• 62-53-3 aniline 
• 100-52-7 benzaldehyde 
• 7568-93-6 2-Amino-1-phenylethanol 
• 36602-06-9 N,N-diphenylamino acetonitrile 
• 538-51-2 benzylidene phenylamine 

Downstream Products

• 127785-95-9 2-Amino-4,5-dihydro-1,5-diphenyl-1H-imidazole hydrobromide 
• 71644-28-5 1,5-diphenylimidazolidin-2-one 
• 105159-20-4 C₄₃H₄₄N₄O₄S₂ 
• 105159-28-2 N-{2-[4-(1,3-Dimethyl-2,4-dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-25-9 N-{2-[4-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105167-93-9 C₂₅H₂₆N₆O₄ 
• 97511-34-7 4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide 
• 97511-33-6 3,4-diphenyl-1-tosylimidazolidine 
• 143538-94-7 (1,5-Diphenyl-4,5-dihydro-1H-imidazol-2-yl)-carbamic acid methyl ester 
• 105159-32-8 4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide 
• 143538-88-9 C₁₉H₂₂N₄O₄ 

Relevant academic research and scientific papers

Synthesis of imidazolidin-2-ones employing dialkyl carbonates as an ecofriendly carbonylation source

A new approach to the synthesis of imidazolidin-2-ones by carbonylation of vicinal diamines with dialkyl carbonates using Pb(NO3)2 and Cu(ii) salts as catalysts has been described in the present protocol. A comparative study using Cu(ii) salts and Pb(NO3)2 as catalysts has suggested Cu(NO3)2 and CuCl 2·2H2O salts to be as promising as Pb(NO 3)2 and can replace the latter in the carbonylation reactions employing dialkyl carbonates. the Partner Organisations 2014.

Highly active and selective supported iron oxide nanoparticles in microwave-assisted N-alkylations of amines with alcohols

Highly active and stable supported iron oxide nanoparticles show excellent activities and switchable selectivities to target products in the microwave-assisted N-alkylation of amines with alcohols. The Royal Society of Chemistry 2010.

NOVEL COMPOUNDS

The present invention relates to compounds and derivatives thereof, their synthesis, and their use as glucocorticoid receptor modulators. The compounds of the instant invention are ligands for glucocorticoid receptors and as such may be useful for treatment or prevention of a variety of conditions related to glucocorticoid functioning including rheumatoid arthritis, osteoarthritis, allery, asthma, pneumonia, dermatitis, eczema, psoriasis, lupus, colitis, inflammatory bowel disease, multiple sclerosis, congenital neutropenia, Wegener's granulomatosis, Addison's Disease, Crohn's disease Cushing Syndrome, or as immunosuppressants in organ transplantation.

Design, synthesis, and pharmacological evaluation of conformationally constrained analogues of N,N'-diaryl- and N-aryl-N-aralkylguanidines as potent inhibitors of neuronal Na+ channels

In the present investigation, the rationale for the design, synthesis, and biological evaluation of potent inhibitors of neuronal Na+ channels is described. N,N'-Diaryl- and N-aryl-Naralkylguanidine templates were locked in conformations mimick

A Convenient Synthesis of 1,2,5-Trisubstituted 4,5-Dihydroimidazoles and 1,3-Diazaspiroalk-2-enes from N-Alkylideneanilines

A convenient synthesis of 5-aryl-4,5-dihydro-2-methoxycarbonylamino-1-phenylimidazoles 5a-d and 2-methoxycarbonylamino-1-phenyl-1,3-diazaspiroalk-2-enes 5e,f has been reported from N-alkylideneanilines 1a-f via cyclization of the corresponding 1,2

ACAT inhibitors

This invention relates to novel compounds which are ACAT inhibitors rendering them useful in lowering blood cholesterol levels. The compounds contain two urea or thiourea, amide, or amine moieties or combinations of said moieties and have the following general formula: wherein Ar is an aryl group, m and n are zero or one,W and YNH and form the urea, thiourea, amide or amine moieties.

MODELS OF FOLATE COENZYMES 16. CHEMICAL MODELLING OF THE THYMIDYLATE SYNTHASE REACTION. EVIDENCE FOR AN "EXOCYCLIC METHYLENE INTERMEDIATE" ANALOGUE, WHICH IS REDUCIBLE TO A THYMINE DERIVATIVE, IN THE REACTION OF 6-AMINOURACILS WITH A 5,10-METHYLENETETRAHY

Reactions of 6-amino-, 6-alkylamino-, and 6-anilino-1,3-dimethyluracils (1a-1e) with 3,4-diphenyl-1-tosylimidazolidine (2), in the presence of acid, lead to the formation of products which are derived from an "exocyclic methylene intermediate" analogous t