97511-33-6

Upstream product

• 42164-54-5 N-(2-amino-1-phenylethyl)benzenamine 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 91-78-1 1,3,5-triphenylhexahydro-1,3,5-triazine 
• 100-62-9 N-methylenebenzenamine 
• 100-42-5 styrene 
• 100-61-8 N-methylaniline 
• 127-65-1 chloroamine-T 
• 62-53-3 aniline 
• 97511-34-7 4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide 
• 21080-09-1 NSC 4573 
• 50-00-0 formaldehyd 
• 105159-32-8 4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide 

Downstream Products

• 105159-19-1 N-{2-[2,4-Bis-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 10146-98-2 6,6'-diamino-1,1',3,3'-tetramethyl-5,5'-(methylene)bis[pyrimidine-2,4(1H,3H)-dione] 
• 105159-32-8 4-methyl-N-(2-phenyl-2-(phenylamino)ethyl)benzenesulfonamide 
• 105159-25-9 N-{2-[4-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-21-5 6-Amino-1,3-dimethyl-5-{4-[5-phenyl-3-(toluene-4-sulfonyl)-imidazolidin-1-yl]-benzyl}-1H-pyrimidine-2,4-dione 
• 13332-78-0 di-(1,3-dimethyl-6-methylaminouracil-5-yl)methane 
• 105159-26-0 N-{2-[4-(1,3-Dimethyl-6-methylamino-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-22-6 1,3-Dimethyl-6-methylamino-5-{4-[5-phenyl-3-(toluene-4-sulfonyl)-imidazolidin-1-yl]-benzyl}-1H-pyrimidine-2,4-dione 
• 105159-20-4 C₄₃H₄₄N₄O₄S₂ 
• 105167-93-9 C₂₅H₂₆N₆O₄ 
• 105159-28-2 N-{2-[4-(1,3-Dimethyl-2,4-dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 97511-34-7 4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide 
• 105205-04-7 N-{2-[4-(6-Benzylamino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-23-7 6-Benzylamino-1,3-dimethyl-5-{4-[5-phenyl-3-(toluene-4-sulfonyl)-imidazolidin-1-yl]-benzyl}-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Access to imidazolidines via 1,3-Dipolar cycloadditions of 1,3,5-triazinanes with aziridines

The unprecedented 1,3-dipolar cycloaddition of 1,3,5-triazinanes and aziridines has been described. With readily available starting material, this method offers efficient access to a wide range of functionalized imidazolidine derivatives in moderate to good yields (up to 92percent) under mild conditions. Preliminary mechanistic investigations show that the ring opened zwitterionic pathway product dominated over the second-order nucleophilic substitution-like product. This protocol is very promising because the reaction is scalable, and gives versatile transformation of the products into other functionalized imidazolidines.

Stereospecific copper-catalyzed domino ring opening and sp3 C-H functionalization of activated aziridines with N-alkylanilines

Copper efficiently catalyzed nucleophilic ring opening, sp3 C-H functionalization, and C-N bond formation in the presence of tert-butyl hydroperoxide to afford functionalized imidazolidines starting from N-sulfonylaziridines and Nalkylanilines. The products were obtained in high optical purities (95 → 99% ee) with excellent functional group tolerance.

on Water C(sp3)-H Functionalization/C-O/C-N Bonds Formations: Synthesis of Functionalized Oxazolidines and Imidazolidines

On water oxidative C(sp3)-H functionalization/C-O/C-N bonds formations using tetrabutylammonium iodide as the catalyst and tert-butyl hydroperoxide in water (T-Hydro) as the oxidant affords a potential route for the construction of functionalized oxazolidines and imidazolidines. The reaction is simple, regioselective, and effective at moderate temperature with broad substrate scope. In the case of optically active substrates, the oxidative cyclization can be accomplished with high optical purities.

MODELS OF FOLATE COENZYMES 16. CHEMICAL MODELLING OF THE THYMIDYLATE SYNTHASE REACTION. EVIDENCE FOR AN "EXOCYCLIC METHYLENE INTERMEDIATE" ANALOGUE, WHICH IS REDUCIBLE TO A THYMINE DERIVATIVE, IN THE REACTION OF 6-AMINOURACILS WITH A 5,10-METHYLENETETRAHY

Reactions of 6-amino-, 6-alkylamino-, and 6-anilino-1,3-dimethyluracils (1a-1e) with 3,4-diphenyl-1-tosylimidazolidine (2), in the presence of acid, lead to the formation of products which are derived from an "exocyclic methylene intermediate" analogous t