42489-57-6

Basic information

• Product Name: 1-chloro-2-(1-methylethoxy)benzene
• Synonyms: 1-chloro-2-(1-methylethoxy)benzene;Nsc26778
• CAS NO: 42489-57-6
• Molecular Formula: C₉H₁₁ClO
• Molecular Weight: 170.63604
• EINECS: 255-850-7
• Mol File: 42489-57-6.mol

Chemical Properties

• Boiling Point: 215.3°Cat760mmHg
• Flash Point: 89.7°C
• Appearance: /
• Density: 1.074g/cm³
• Vapor Pressure: 0.218mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: 1-chloro-2-(1-methylethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-(1-methylethoxy)benzene(42489-57-6)
• EPA Substance Registry System: 1-chloro-2-(1-methylethoxy)benzene(42489-57-6)

Safety Data

• Hazardous Substances Data: 42489-57-6(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
1-chloro-2-(1-methylethoxy)benzene is used as an intermediate in the production of pesticides, pharmaceuticals, and other organic compounds. It serves as a key building block for the synthesis of various chemical products due to its versatile chemical structure.
Used in Research and Laboratory Settings:
1-chloro-2-(1-methylethoxy)benzene is also used as a research chemical and in laboratory settings for various purposes. It aids scientists in conducting experiments and developing new methods or products in the fields of chemistry and related disciplines.
It is important to handle 1-chloro-2-(1-methylethoxy)benzene with caution, as it can be harmful if inhaled, ingested, or in contact with skin and eyes. Proper safety measures should be taken when working with this chemical to ensure the well-being of individuals and the environment.

InChI:InChI=1/C9H11ClO/c1-7(2)11-9-6-4-3-5-8(9)10/h3-7H,1-2H3

Upstream product

• 473-34-7 N,N-dichloro-p-toluenesulfonamide 
• 2741-16-4 isopropoxybenzene 
• 64-19-7 acetic acid 
• 95-57-8 2-monochlorophenol 
• 75-26-3 isopropyl bromide 
• 67-63-0 isopropyl alcohol 
• 95-50-1 1,2-dichloro-benzene 

Downstream Products

• 32695-20-8 2-chloro-4-(chloromethyl)-1-(1-methylethoxy)benzene 
• 64360-46-9 [4-(3-Chloro-4-isopropoxy-benzyloxy)-3-methyl-phenyl]-acetic acid 
• 64360-37-8 [4-(3-Chloro-4-isopropoxy-benzyloxy)-phenyl]-acetic acid 
• 60736-69-8 3-chloro-4-(3'-chloro-4'-isopropoxybenzyloxy) phenylacetic acid 
• 102163-68-8 {2-chloro-4-[4-(3-chloro-propyl)-benzyl]-phenyl}-isopropyl ether 

Relevant articles and documents

PHASE-TRANSFER NUCLEOPHILIC AROMATIC SUBSTITUTION OF Cr(CO)3-COMPLEXED DICHLOROBENZENES WITH ALCOHOLS

Cr(CO)-complexed ortho- and para-dichlorobenzenes react with primary and secondary alcohols, in the presence of KOH, under phase-transfer conditions to give monosubstitution products only.The meta isomer affords disubstitution products also.The same reaction, carried out in DMSO with alcohols in excess, leads in all cases to dialkoxy derivatives.Factors potentially influencing the reactivity of Cr(CO)3-complexed ortho-, meta-, and para-dichlorobenzenes are discussed.

POLY(ETHYLENE GLYCOL)S AS PHASE TRANSFER CATALYSTS IN THE ALKOXYLATION OF HALOBENZENES OF ALKYL ARYL ETHERS

Mono and di-halobenzenes and alkoxide ions gave monoalkoxybenzenes, but no phenols, when catalyzed by high molecular weight poly(ethylene glycol)s as phase transfer catalysts.Bromobenzenes were more reactive than chlorobenzenes but gave more side products, and for alcohols the reactivity was primary>secondary>tertiary.