4253-68-3

Basic information

• Product Name: D-(+)-GLUCONO-1,5-LACTONE
• Synonyms: (3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-one;1,2,3,4,5-PENTAHYDROXYCAPROIC ACID DELTA-LACTONE;GLUCONIC ANHYDRIDE;GLUCONIC-D-LACTONE;GLUCONO-1,5-LACTONE;GLUCONO-D-LACTONE;GLUCONOLACTONE;GLUCONIC ACID, ANHYDRIDE
• CAS NO: 4253-68-3
• Molecular Formula: C6H10O6
• Molecular Weight: 178.14
• EINECS: 202-016-5
• Product Categories: Sugars, Carbohydrates & Glucosides
• Mol File: 4253-68-3.mol
• Article Data: 119

Chemical Properties

• Melting Point: 160 °C (dec.)(lit.)
• Appearance: /
• CAS DataBase Reference: D-(+)-GLUCONO-1,5-LACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: D-(+)-GLUCONO-1,5-LACTONE(4253-68-3)
• EPA Substance Registry System: D-(+)-GLUCONO-1,5-LACTONE(4253-68-3)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: LZ5184000
• F: 21
• Hazardous Substances Data: 4253-68-3(Hazardous Substances Data)

Usage

General Description

D-(+)-GLUCONO-1,5-LACTONE is a naturally occurring compound and is the cyclic ester of D-gluconic acid. It is a white, odorless powder that is soluble in water and has a slightly acidic taste. D-(+)-GLUCONO-1,5-LACTONE is commonly used as an acidity regulator in food and beverage products, as well as a leavening agent in baking. It is also used as a sequestrant and chelating agent in various industrial applications. Additionally, D-(+)-GLUCONO-1,5-LACTONE has antioxidant properties and is used in the cosmetic and pharmaceutical industries for its ability to prevent oxidation and extend shelf life.

Upstream product

• 642-99-9 mannonic acid 
• 3458-28-4 D-Mannose 
• 526-95-4 gluconic acid 
• 74421-63-9 ethyl D-mannonate 
• 50-99-7 D-glucose 
• 7732-18-5 water 
• 7726-95-6 bromine 
• 50-70-4 D-sorbitol 
• 740753-96-2 L-allonic acid 
• 133-42-6 D-galactonic acid 
• 59-23-4 D-Galactose 
• 133-42-6 L-mannonic acid 
• 90405-08-6 methyl 2,3-O-isopropylidene-β-D-gulofuranosiduronic acid 
• 1022160-11-7 L-gluconic acid ; potassium-compound 

Downstream Products

• 6067-21-6 methyl 2,3,4,6-tetra-O-acetyl-D-gluconate 
• 97022-92-9 1-<4-Dimethylamino-benzyl>-2-D-gluconoyl-hydrazin 
• 3118-85-2 D-gluconamide 
• 24758-61-0 N-propylgluconamide 
• 73485-90-2 <1-(2)H>-1,2,3,4,6-penta-O-acetyl-β-D-glucopyranose 
• 190182-44-6 Acetic acid (2R,3S)-6-oxo-5-(toluene-4-sulfonyloxy)-2-(toluene-4-sulfonyloxymethyl)-3,6-dihydro-2H-pyran-3-yl ester 
• 24758-68-7 phenylhydrazide of D-gluconic acid 
• 92701-16-1 1-Benzylidenamino-2-D-gluconoylamino-aethan 
• 93722-08-8 1-m-Nitro-benzylidenamino-2-D-gluconoylamino-aethan 
• 106683-77-6 N-(β-D-Dluconylamino-ethyl)-phthalsaeure-monoamid 
• 101320-36-9 Terephthalaldehyd-bis-(β-D-gluconoylamino-ethyl-α-imin) 
• 93737-22-5 1-p-Dimethylamino-benzylidenamino-2-D-gluconoyl-amino-aethan 
• 1360568-71-3 (2S,3R,4S,5S,6R)2-(4-chloro-3-(4-((1-ethylcyclopentyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol 
• 1360568-73-5 (2R,3R,4S,5S,6R)-2-(4-chloro-3-(4-((1-ethylcyclopentyl)methoxy)benzyl)phenyl)-6-(hydroxymethyl)2methoxytetrahydro-2H-pyran-3,4,5-triol 

Relevant articles and documents

Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4-oxadiazole-2(3H)-thione ligands derived from δ-D-gluconolactone

Four gold(I) complexes conceived as anticancer agents were synthesized by reacting [Au(PEt3)Cl] and [Au(PPh3)Cl] with ligands derived from δ-d-gluconolactone. The ligands’ structure was designed to combine desired biological properti

Synthesis of Cu(OH)F microspheres using atmospheric dielectric barrier discharge microplasma: a high-performance non-enzymatic electrochemical sensor

In this study, Cu(OH)F microspheres suppported on a carbon cloth (Cu(OH)F MS/CC) were rapidly synthesized (at 90 V with 20 min) using an atmospheric dielectric barrier discharge microplasma (DBD). As a multifunctional electrochemical sensor for the detection of glucose (Glu), formaldehyde and hydrogen peroxide, it can accurately detect blood glucose levels in actual serum samples and can determine the contents of formaldehyde and hydrogen peroxide in water samples. Furthermore, it shows good sensitivity and selectivity, which confirmed the feasibility of the Cu(OH)F microsphere electrode for electrochemical sensing. This method was not only rapid and mild (at room temperature and atmospheric pressure) but also provided a promising route for the preparation of nanomaterials for electrochemical sensors.

carba Nicotinamide Adenine Dinucleotide Phosphate: Robust Cofactor for Redox Biocatalysis

Here we report a new robust nicotinamide dinucleotide phosphate cofactor analog (carba-NADP+) and its acceptance by many enzymes in the class of oxidoreductases. Replacing one ribose oxygen with a methylene group of the natural NADP+ was found to enhance stability dramatically. Decomposition experiments at moderate and high temperatures with the cofactors showed a drastic increase in half-life time at elevated temperatures since it significantly disfavors hydrolysis of the pyridinium-N?glycoside bond. Overall, more than 27 different oxidoreductases were successfully tested, and a thorough analytical characterization and comparison is given. The cofactor carba-NADP+ opens up the field of redox-biocatalysis under harsh conditions.