4394-54-1

Upstream product

• 766-51-8 2-Chloroanisole 
• 79-03-8 propionyl chloride 
• 36590-49-5 3-chloro-4-methoxybenzoyl chloride 
• 89978-93-8 3-chloro-4-methoxy-benzoic acid amide 
• 37908-98-8 methyl 3-chloro-p-anisate 
• 37908-96-6 3-chloro-4-methoxy benzoic acid 
• 4903-09-7 3-chloro-4-methoxy-benzaldehyde 
• 213470-63-4 (+/-)-1-(3'-chloro-4'-methoxyphenyl)-1-propanol 
• 123-62-6 propionic acid anhydride 
• 925-90-6 ethylmagnesium bromide 
• 102151-33-7 3-Chloro-4-methoxybenzonitrile 

Downstream Products

• 102976-53-4 2-Bromo-1-(3-chloro-4-methoxy-phenyl)-propan-1-one 
• 85720-36-1 cis-3,4-bis(3-chloro-4-methoxyphenyl)hex-3-ene 
• 1857-56-3 3-(3-chloro-4-methoxyphenyl)propionic acid 
• 169217-47-4 (+/-)-(1R,2S)-1-(3'-chloro-4'-methoxyphenyl)-1,2-propanediol 
• 108619-53-0 meso-3,3'-Dichlorhexestrol 
• 94804-95-2 meso-3,4-Bis(3-chlor-4-methoxyphenyl)hexan 
• 4394-43-8 α-Amino-3-chlor-4-methoxy-propiophenon 
• 13726-29-9 β-(3-Chlor-4-methoxy-phenyl)-propionyl-homoveratrylamin 
• 213470-67-8 1-(3-Chloro-4-methoxy-phenyl)-2-hydroxy-propan-1-one 
• 4394-53-0 3-Chlor-4-methoxy-α-hydroxyimino-propiophenon 
• 2892-27-5 3'-chloro-4'-hydroxypropiophenone 

Relevant academic research and scientific papers

Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from Bjerkandera species

Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1- (3',5'-dichloro-4'-methoxyphenyl)-1,2-propanediol (2) and 1-(3'-chloro-4'- methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp, BOS55 was also a new finding.

Design and synthesis of a hapten for the radioimmunoassay of bupropion

The synthesis of a hapten useful in the radioimmunoassay of bupropion is described. Since bupropion has no functional group that can be easily derivatized, a hydroxypropyl group was incorporated into the molecule. Studies in cross-reactivity with possible metabolites required the synthesis of the 4'-hydroxy analogue of bupropion. This synthesis is also described.

ACYLATION OF CHLOROANISOLES

In the reaction of 2-, 3-, and 4-chloroanisoles with the chlorides and anhydrides of acetic, propionic, and 4-substituted benzoic acids in the presence of 1E-3 mole of ferric chloride 35-80percent of the ketone fraction was obtained.Under the reaction con