4468-47-7

Usage

Uses

Used in the Food Industry:
2-Cyano-3-butanone is used as a flavoring agent for its distinctive fruity aroma, enhancing the taste and appeal of various food products.
Used in Pharmaceutical Synthesis:
As an intermediate, 2-Cyano-3-butanone plays a crucial role in the synthesis of pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Agrochemical Production:
2-CYANO-3-BUTANONE is also utilized as an intermediate in the production of agrochemicals, aiding in the creation of substances that protect and enhance crop yields.
Used in Organic Chemistry as a Building Block:
2-Cyano-3-butanone is employed in the synthesis of a wide range of organic compounds, showcasing its versatility and importance in the field of organic chemistry.
Used as a Solvent:
In various chemical processes, 2-Cyano-3-butanone serves as a solvent, facilitating reactions and improving the efficiency of chemical syntheses.
Used as a Reagent in Organic Synthesis Reactions:
2-CYANO-3-BUTANONE functions as a reagent in numerous organic synthesis reactions, enabling the formation of complex molecules and contributing to the advancement of chemical research and development.

Upstream product

• 7064-40-6 4,5-dimethyl-isoxazole 
• 4433-76-5 2-methyl-3-oxobutanamide 
• 143-33-9 sodium cyanide 
• 4091-39-8 3-chloro-2-butanone 
• 151-50-8 potassium cyanide 
• 141-78-6 ethyl acetate 
• 107-12-0 propiononitrile 
• 19483-78-4 3-amino-2-methyl-2-butenenitrile 
• 13435-20-6 tetraethylammoniumcyanide 
• 75-05-8 acetonitrile 
• 19481-82-4 2-bromopropionitrile 
• 814-75-5 3-bromo-butanone 
• 75-36-5 acetyl chloride 
• 64-17-5 ethanol 

Downstream Products

• 51143-42-1 3,4-dimethyl-1-phenyl-1H-pyrazol-5-amine 
• 19947-75-2 5-amino-3,4-dimethylisoxazol 
• 4433-76-5 2-methyl-3-oxobutanamide 
• 36931-70-1 4,5-dimethyl-2-(3-phenyl-isoxazol-5-yl)-2H-pyrazol-3-ylamine 
• 37719-02-1 2,2-dimethyl-3-oxobutanenitrile 
• 82471-44-1 2-Acetyl-2-methyl-succinonitrile 
• 230646-11-4 ethyl 3-amino-4,5-dimethyl-1H-pyrrole-2-carboxylate 
• 230646-12-5 Ethyl (E)-3-(cinnamoylamino)-4,5-dimethylpyrrole-2-carboxylate 
• 6613-46-3 cis-2,3-Dicarbodinitril-2-buten 
• 91567-74-7 N-(3,4-dimethyl-isoxazol-5-yl)-toluene-4-sulfonamide 
• 127-69-5 sulfisoxazole 
• 4206-74-0 N⁴-Acetyl-N¹-<3.4-dimethyl-5-isoxazolyl>-sulfanilamid 
• 1247725-90-1 4'-[(2-propyl-1H-benzimidazol-1-yl)methyl]-N-(3,4-dimethyl-5-isoxazolyl)-[1,1'-biphenyl]-2-sulfonamide 
• 1247725-91-2 4'-[(2-butyl-1H-benzimidazol-1-yl)methyl]-N-(3,4-dimethyl-5-isoxazolyl)-[1,1'-biphenyl]-2-sulfonamide 

Relevant academic research and scientific papers

Synthesis and biological evaluation of 4′-[(benzimidazole-1-yl) methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists

A series of 4′-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives (Ia-Il) were synthesized and biologically evaluated. It was found that Ig, the most active compound, antagonized both Ang II AT1 and endothelin ETA receptors (AT1 IC50 = 8.5, ETA IC50 = 8.9 nM), and was more potent than losartan in RHRs with no significant effect on heart rate. The preliminary structure-activity relationships were also discussed in the present paper.

Process for poducing beta-oxonitrile compound or alkali metal salt thereof

The present invention relates to a process for preparing a β-oxonitrile compound or an alkali metal salt thereof which comprises reacting a carboxylic ester represented by the formula (1): R1CO2R2??(1) wherein R1 /su

Synthesis of 3-Oxo-8-oxabicyclooct-6-ene-2-carbonitriles from γ-Bromo-β-oxonitriles and Furan via Cycloaddition of 1-Cyanoallylium-2-olates

Some γ-bromo-β-oxonitriles 3 react with furan in the presence of silver oxide to form stereoselectively the title compounds 7.Satisfying yields are obtained only with those bromides 3, whose γ-carbon is tertiary or which are monoalkylated both at the α- and γ-carbon atoms.The results are explained by a cycloaddition of 1-cyanoallylium-2-olate intermediates (14) to the 1,3-diene system of the furan.With cyclic γ-bromo-β-oxonitriles (6) two types of cycloadducts were observed: 3-bromo-3-methyl-2-oxocyclohexanecarbonitrile (6b) and 3-bromo-2-oxocyclododecanecarbonitrile (6d) form the tricyclic cycloadduts 10b and d, analogs of the bicyclic adducts 7.With 3-bromo-2-oxocyclohexanecarbonitrile (6a) and 3-bromo-5-tert-butyl-2-oxocyclohexanecarbonitrile (6e), however, the carbonyl oxygen is connected with an α-carbon of the furan to give the tricyclic cycloadducts 12Aa and Ae.The structure endo-2,endo-4-dimethyl-3-oxo-8-oxabicyclooct-6-ene-exo-2-carbonitrile (7eα) was determined by X-ray analysis.