4520-29-0

Basic information

• Product Name: [benzene-1,3-diylbis(oxy)]bis(trimethylsilane)
• Synonyms: 1,3-Bis(trimethylsiloxy)benzene
• CAS NO: 4520-29-0
• Molecular Formula: C₁₂H₂₂O₂Si₂
• Molecular Weight: 254.4729
• Mol File: 4520-29-0.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 239.2°C at 760 mmHg
• Flash Point: 82.6°C
• Density: 0.925g/cm³
• Vapor Pressure: 0.0626mmHg at 25°C
• Refractive Index: 1.461
• CAS DataBase Reference: [benzene-1,3-diylbis(oxy)]bis(trimethylsilane)(CAS DataBase Reference)
• NIST Chemistry Reference: [benzene-1,3-diylbis(oxy)]bis(trimethylsilane)(4520-29-0)
• EPA Substance Registry System: [benzene-1,3-diylbis(oxy)]bis(trimethylsilane)(4520-29-0)

Safety Data

• Hazardous Substances Data: 4520-29-0(Hazardous Substances Data)

Usage

General Description

Benzene-1,3-diylbis(oxy)]bis(trimethylsilane), also known as bis(trimethylsilyl)benzene-1,3-diol, is a chemical compound with the molecular formula C14H26O2Si2. It is a colorless liquid with a boiling point of 244-245°C. [benzene-1,3-diylbis(oxy)]bis(trimethylsilane) is primarily used as a crosslinking agent in the production of silicone rubber and as a coupling agent in the synthesis of organosilicon compounds. Additionally, it can be used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals and agricultural chemicals. Bis(trimethylsilyl)benzene-1,3-diol is flammable and should be handled with care, as exposure to high temperatures or flames may cause it to decompose and produce hazardous fumes.

Upstream product

• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 108-46-3 recorcinol 
• 3385-94-2 hexamethyldisilathiane 
• 17882-01-8 3-trimethylsilanyloxy-phenol 
• 75-77-4 chloro-trimethyl-silane 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 32115-55-2 N,N-Dimethylcarbamidsaeure-trimethylsilylester 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 

Downstream Products

• 108-46-3 recorcinol 
• 1228552-11-1 C₁₈H₃₃BO₄Si₂ 
• 75-76-3 tetramethylsilane 
• 107-46-0 Hexamethyldisiloxane 
• 85708-07-2 1,3-Bis-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)benzene 
• 124647-06-9 2,4-dihydroxy-1-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-benzene 
• 82300-66-1 2,4-dihydroxy-1-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-benzene 

Relevant articles and documents

Synthesis and characterization of a bifunctional nanomagnetic solid acid catalyst (Fe3O4@CeO2/SO42?) and investigation of its efficiency in the protection process of alcohols and phenols via hexamethyldisilazane under solvent-free conditions

In this research, Fe3O4@CeO2 (FC) was synthesized using the coprecipitation method and functionalized by an ammonium sulfate solution to achieve a heterogeneous solid acid Fe3O4@CeO2/SO42? (FCA) catalyst. The synthesized bifunctional catalyst was used in the protection process of alcohols and phenols using hexamethyldisilazane (HMDS) at ambient temperature under solvent-free conditions. Due to its excellent magnetic properties, FCA can easily be separated from the reaction mixture and reused several times without significant loss in its catalytic activity. Excellent yield and selectivity, simple separation, low cost, and high recyclability of the nanocatalyst are outstanding advantages of this procedure. The characterization was carried out using different techniques such as Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and vibrating sample magnetometry (VSM).

Nano Fe3O4@ZrO2/SO42?: A highly efficient catalyst for the protection and deprotection of hydroxyl groups using HMDS under solvent-free condition

In this work, we introduce a new procedure for the protection and deprotection process of various types of alcohols and phenols by HMDS in the presence of nano magnetic sulfated zirconia (Fe3O4@ZrO2/SO42?) as a solid acid catalyst under very mild and solvent-free condition. This method has interesting advantages like short reaction times and a simple workup process. With regard to some outstanding benefits of this new heterogeneous catalyst such as excellent yield, reusability of the catalyst and easy thermal stability, high acidity, strong and excellent magnetic properties, this method can be very interesting in aspect of green chemistry Principles.

Highly efficient and selective trimethylsilylation of alcohols and phenols with hexamethyldisilazane catalyzed by polystyrene-bound tin(IV) porphyrin

In the present work, investigation of the catalytic activity of tetrakis(p-aminophenyl)porphyrinatotin(IV) trifluoromethanesulfonate, [Sn IV(TNH2PP)(OTf)2], supported on chloromethylated polystyrene in the trimethylsilylation of alcohols and phenols with hexamethyldisilazane is reported. The prepared catalyst was characterized by elemental analysis, FT-IR and diffuses reflectance UV-Vis spectroscopic methods. This catalyst was used for selective trimethylsilylation of different alcohols and phenols with HMDS, with short reaction times and high yields. Also the catalyst is of high reusability and stability, in that it was recovered several times without loss of its initial activity.