46185-83-5

Basic information

• Product Name: 2-ETHOXY-8-METHOXYQUINOLINE
• Synonyms: 2-ETHOXY-8-METHOXYQUINOLINE;2-Ethoxyquinoline
• CAS NO: 46185-83-5
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 203.23712
• Mol File: 46185-83-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 271.6°Cat760mmHg
• Flash Point: 99.6°C
• Appearance: /
• Density: 1.101g/cm³
• Vapor Pressure: 0.0106mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 2-ETHOXY-8-METHOXYQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ETHOXY-8-METHOXYQUINOLINE(46185-83-5)
• EPA Substance Registry System: 2-ETHOXY-8-METHOXYQUINOLINE(46185-83-5)

Safety Data

• Hazardous Substances Data: 46185-83-5(Hazardous Substances Data)

Usage

General Description

2-Ethoxy-8-methoxyquinoline is a chemical compound that belongs to the family of quinolines, which are aromatic compounds with two fused six-membered rings. This specific molecule has an ethoxy group attached to the second position of the quinoline structure and a methoxy group on the eighth position. Due to its quinoline base, it may possess a broad range of biological activities, such as antimicrobial and antifungal properties, which make it potentially useful in the field of medicine. However, detailed information about its physical properties, health hazards, and other specific applications is limited and requires further research.

InChI:InChI=1/C11H11NO/c1-2-13-11-8-7-9-5-3-4-6-10(9)12-11/h3-8H,2H2,1H3

Upstream product

• 1613-37-2 Quinoline N-oxide 
• 98-59-9 p-toluenesulfonyl chloride 
• 2942-58-7 diethyl cyanophosphonate 
• 64-17-5 ethanol 
• 612-62-4 2-Chloroquinoline 
• 16331-64-9 ethanolate 
• 59-31-4 2-quinolone 
• 75-03-6 ethyl iodide 

Downstream Products

• 7661-39-4 2-n-butylquinoline 
• 88284-13-3 2-ethoxy-quinoline-3-carboxylic acid 
• 34786-24-8 ethyl 3-methylphenyl sulphide 
• 622-38-8 Ethyl phenyl sulfide 
• 59-31-4 2-hydroxyquinoline 
• 74-85-1 ethene 
• 59-31-4 2-quinolone 
• 53761-50-5 1-Ethyl-1,2-dihydrochinolin-2-on 
• 75-00-3 chloroethane 

Relevant articles and documents

H-phosphonate-mediated sulfonylation of heteroaromatic N-oxides: a mild and metal-free one-pot synthesis of 2-sulfonyl quinolines/pyridines

A smart H-phosphonate-mediated synthetic strategy for the sulfonylation of heteroaromatic N-oxides has been developed, by which a large variety of 2-sulfonyl quinolines/pyridines were synthesized starting from easily available sulfonyl chlorides, diisopropyl H-phosphonate and pyridine/quinoline N-oxides in one pot under metal-free conditions at room temperature.

Hydrogen Atom Transfer Oxidation of Primary and Secondary Alcoholates into Aldehydes and Ketones by Aromatic Halides in Liquid Ammonia. A New Electrochemically Induceable Reaction

It is possible to induce the oxidation of alcoholates into the corresponding carbonyl compounds by electrochemical reduction of aromatic halides in liquid ammonia, i.e., to electrochemically trigger the reaction ArX + >CH-O- -> ArH + >C=O + X-.H-Atom transfer from the acoholate to the aryl radical formed upon reduction of the aryl halide appears as the key step of the oxidation process.The ketyl anion radical thus formed can be oxidized into the parent carbonyl compound, remain electrochemically stable, or be reduced into the dianion depending upon the location of the two corresponding standard potentials toward the reduction potential of the aryl halide.Electricity consumption thus tends toward 0, 1, and 2 F/mol for the three cases, respectively.The reactions competing with H-atom transfer, thus lowering the efficiency of the electrochemical inducement of the oxidation process, are electron transfer to the aryl radical which occur at the electrode surface and/or in the solution.These will play the role of termination steps for the corresponding chain system involving homogeneous initiation of the reaction.The kinetic analysis of the competition between H-atom transfer and homogeneous or heterogeneous electron transfer allows a detailed investigation of the reaction mechanism by electrochemical techniques such as cyclic voltammetry.This also leads to the determination of the rate constants of H-atom transfer of the alcoholate-aryl radical couple.