4641-67-2

Basic information

• Product Name: 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL
• Synonyms: 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL
• CAS NO: 4641-67-2
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.3
• Mol File: 4641-67-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL(4641-67-2)
• EPA Substance Registry System: 1-PHENYL-3-(PYRROLIDIN-1-YL)PROPAN-1-OL(4641-67-2)

Safety Data

• Hazardous Substances Data: 4641-67-2(Hazardous Substances Data)

Usage

Class

Secondary amine, Alcohol

Structure

Contains a phenyl group attached to a pyrrolidin-1-yl group, which is attached to a propan-1-ol group.

Usage

Organic synthesis, pharmaceutical research (building block for the synthesis of various drugs and pharmaceutical compounds)

Potential applications

Medicinal chemistry, drug discovery (due to unique chemical structure and properties)

Upstream product

• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 936-59-4 3-chloropropiophenone 
• 123-75-1 pyrrolidine 
• 62872-58-6 3-iodo-1-phenyl-propan-1-ol 
• 94-39-3 1-phenyl-3-(pyrrolidin-1-yl)propan-1-one 
• 98-86-2 acetophenone 

Downstream Products

• 157846-67-8 Methanesulfonic acid 1-phenyl-3-pyrrolidin-1-yl-propyl ester 
• 1373610-96-8 1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)pyrrolidine 
• 1384515-30-3 2-phenylhexahydro-2H-pyrrolo[2,1-b][1,3]oxazine 
• 157846-79-2 1-[3-(3,4-Dimethoxy-phenoxy)-3-phenyl-propyl]-pyrrolidine 
• 157846-76-9 1-[3-(2-Methoxy-phenoxy)-3-phenyl-propyl]-pyrrolidine 
• 157846-78-1 1-[3-(4-Methoxy-phenoxy)-3-phenyl-propyl]-pyrrolidine 
• 157846-77-0 1-[3-(3-Methoxy-phenoxy)-3-phenyl-propyl]-pyrrolidine 
• 42796-29-2 1-(3-Phenoxy-3-phenyl-propyl)-pyrrolidine 

Relevant articles and documents

Electrooxidative cyclization of hydroxyamino compounds possessing a benzyl group

Several novel 2-aryl-1,3-oxazinane and 2-aryl-1,3-oxazolidine derivatives were synthesized from N-benzyl-2-piperidineethanols and N-benzyl-2- piperidinemethanols, respectively, by using electrooxidative methods in methanol. For these reactions, the yields of the corresponding cyclized compounds were significantly increased by using catalytic amounts of iodide ions. In contrast, 3-dialkylamino-1-phenylpropanols afforded the expected cyclic 6-phenyl-1,3-oxazinane derivatives using only a small excess of base. Georg Thieme Verlag Stuttgart · New York.

Synthesis of 3-aryloxy-3-phenylpropanamines as possible antidepressants

Thirteen new 3-aryloxy-3-phenylpropanamines (11-23) have been prepared and their structures elucidated by mass, IR and 1H-NMR spectra and by elemental analysis.Being structurally similar to fluoxetine these compounds have been tested for their effect on g