4656-80-8

Basic information

• Product Name: DIPHENYLARSENIC ACID
• Synonyms: hydroxydiphenyl-arsineoxid;kyselinadifenylarsinita;diphenylarsonic acid;DIPHENYLARSINIC ACID;DIPHENYLARSENIC ACID;diphenyl-arsinicaci
• CAS NO: 4656-80-8
• Molecular Formula: C₁₂H₁₁AsO₂
• Molecular Weight: 294.13
• Mol File: 4656-80-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: approximate 170℃
• Boiling Point: 437.9°Cat760mmHg
• Flash Point: 196°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 1.92E-08mmHg at 25°C
• PKA: 4.82±0.70(Predicted)
• CAS DataBase Reference: DIPHENYLARSENIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIPHENYLARSENIC ACID(4656-80-8)
• EPA Substance Registry System: DIPHENYLARSENIC ACID(4656-80-8)

Safety Data

• Hazardous Substances Data: 4656-80-8(Hazardous Substances Data)

Usage

General Description

Diphenylarsenic acid, also known as diphenylarsinic acid, is a chemical compound with the molecular formula C12H11AsO3. It is a white solid and is insoluble in water. DIPHENYLARSENIC ACID is commonly used as a pesticide and herbicide. It works by disrupting the function of an enzyme involved in the synthesis of amino acids, leading to the death of the targeted plants or pests. However, it is also highly toxic to humans and animals, and exposure to diphenylarsenic acid can cause serious health effects, including skin and eye irritation, respiratory problems, and damage to the nervous system. Due to its toxicity and environmental persistence, the use and production of diphenylarsenic acid have been restricted or banned in many countries.

InChI:InChI=1/C12H11AsO2/c14-13(15,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H,14,15)

Upstream product

• 603-32-7 triphenyl-arsane 
• 29165-89-7 trichlorodiphenylarsorane 
• 6309-25-7 bis-(4-amino-phenyl)-arsinic acid 
• 38338-43-1 tribromo-diphenyl-arsorane 
• 21380-83-6 acetyl-diphenyl-arsine 
• 7732-18-5 water 
• 24582-60-3 C₁₄H₁₅AsS 
• 587-85-9 diphenylmercury(II) 
• 100-34-5 benzene diazonium chloride 
• 98-05-5 phenylarsonic acid 
• 2684-02-8 benzenediazonium 
• 696-28-6 dichlorophenylarsine 
• 62-53-3 aniline 
• 15367-57-4 phenyl diphenylthioarsinite 

Downstream Products

• 29165-89-7 trichlorodiphenylarsorane 
• 829-83-4 diphenylarsane 
• 712-48-1 chlorodiphenylarsine 
• 2215-36-3 tetraphenyl-diarsane 
• 2215-16-9 bis(diphenylarsino)oxide 
• 124734-98-1 bis-diphenylarsino-disulfane 
• 108847-23-0 bis-(3-nitro-phenyl)-arsinic acid 
• 108-90-7 chlorobenzene 
• 64448-09-5 benzyl diphenylarsinate 
• 7065-18-1 diphenylarsenic(III) iodide 
• 105976-28-1 Tripropylstannyl-diphenylarsinat 
• 13302-09-5 Tributylstannyl-diphenylarsinat 
• 24385-46-4 trimethyltin diphenylarsinate 
• 38338-43-1 tribromo-diphenyl-arsorane 

Relevant articles and documents

Oral administration of diphenylarsinic acid, a degradation product of chemical warfare agents, induces oxidative and nitrosative stress in cerebellar Purkinje cells

A new clinical syndrome with prominent cerebellar symptoms in patients living in Kamisu City, Ibaraki Prefecture, Japan, is described. Since the patients ingested drinking water containing diphenylarsinic acid (DPA), a stable degradation product of both diphenylcyanoarsine and diphenylchloroarsine, which were developed for use as chemical weapons and cause severe vomiting and sneezing, DPA was suspected of being responsible for the clinical syndrome. The purpose of the present study was to elucidate prominent cerebellar symptoms due to DPA. The aim of the study was to determine if single (15 mg/kg) or continuous (5 mg/kg/day for 5 weeks) oral administration of DPA to ICR-strain mice induced oxidative and/or nitrosative stress in their brain. Significantly positive staining with malondialdehyde (MDA) and 3-nitrotyrosine (3-NT) was observed in the cerebellar Purkinje cells by repeated administration (5 mg/kg/day) with DPA for 5 weeks that led to the cerebellar symptoms from a behavioral pharmacology standpoint and by single administration of DPA (15 mg/kg). Furthermore, it is possible that the production of 3-NT was not caused by peroxynitrite formation. The present results suggest the possibility that arsenic-associated novel active species may be a factor underlying the oxidative and nitrosative stress in Purkinje cells due to exposure to DPA, and that the damage may lead to the cerebellar symptoms.

ORGANOARSENIC COMPOUNDS WITH AN As=N BOND. XIII. TAUTOMERISM OF As,As,N,N'-TETRAARYLARSINIMIDIC AMIDES

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ORGANOARSENIC COMPOUNDS WITH AN As=N BOND. VIII. REACTIVITY OF As,As,N,N'-TETRAARYLARSINIMIDIC AMIDES

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