474-60-2

Basic information

• Product Name: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-
• Synonyms: (3β,5α,24R)-Ergostan-3-ol;24β-Methylcholestanol;5α-Cholestan-20(α/β)-Methyl-3β-ol-25,26,26,26,27,27,27-d7;5α-DihydrocaMpesterol;5α-Cholestan-24(RS)-Methyl-3β-ol;Dihydro-Neospongosterol;Ergostan-3-ol, (3.beta.,5.alpha.,24R)-;(3b,5a,24R)-ergostan-3-ol
• CAS NO: 474-60-2
• Molecular Formula: C₂₈H₅₀O
• Molecular Weight: 402.7
• Product Categories: Pharmaceuticals;Steroids;Intermediates & Fine Chemicals
• Mol File: 474-60-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 461.4°C at 760 mmHg
• Flash Point: 193°C
• Appearance: /
• Density: 0.951g/cm³
• Vapor Pressure: 1.87E-10mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(474-60-2)
• EPA Substance Registry System: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(474-60-2)

Safety Data

• Hazardous Substances Data: 474-60-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 474-60-2 differently. You can refer to the following data:
1. A phytosterol
2. Campestanol can be used as analyte in biological and analytical studies for the determination of 22 natural brassinosteroids in a minute sample of plant tissue by UHPLC-ESI-MS/MS.

InChI:InChI=1/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1

Upstream product

• 135818-30-3 (24R)-α-methyl-5α-cholest-8(14)-en-3β-ol acetate 
• 1900-53-4 (10R)-3c-Acetoxy-10r.13c-dimethyl-17c-((1S:4R)-1.4.5-trimethyl-hexyl)-(8cH.9tH.14tH)-Δ⁵-tetradecahydro-1H-cyclopenta[a]phenanthren 
• 139403-47-7 campesterol 
• 474-63-5 24-methylene cholesterol 
• 95062-29-6 (20R)-24-methylenecholest-5-ene-3β,21-diol 
• 474-62-4 Campesterol 
• 5813-65-0 (22E,24S)-24-methylcholest-22-en-3β-ol 
• 13000-50-5 24-methylene cholesteryl acetate 
• 1900-53-4 campesteryl acetate 
• 53139-27-8 5α.24β_FH-ergosten-(22t)-yl-(3β)-acetate 
• 4087-13-2 5α.24β_FH-ergosten-(14)-yl-(3β)-acetate 
• 1449-60-1 5α.10α-ergostadien-(7.22t)-yl-(3β)-acetate 
• 1105-11-9 5α.10α-ergostadien-(7.22t)-ol-(3β) 
• 1105-11-9 5α.10α-ergostadien-(7.22t)-ol-(3α) 

Downstream Products

• 677324-56-0 C₃₇H₅₆O₄ 
• 677324-57-1 C₃₈H₅₈O₄ 
• 116282-74-7 O-(3.5-dinitro-benzoyl)-campestanol 
• 6424-44-8 O-Benzoyl-haliclonastanol 

Relevant articles and documents

Identification of 5α-stanols in patients with sitosterolemia and xanthomatosis: Stereochemistry of the protonolysis of steroidal organoboranes

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Novel sterol/stanol phosphorylnitroderivatives and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders

Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.

Steroids from the Starfish Euretaster insignis: A Novel Group of Sulphated 3β,21-Dihydroxysteroids

The aqueous extracts of the starfish Euretaster insignis contain two groups of sterol sulphates.The more polar compounds are sulphated 3β,21-dihydroxysteroids; after solvolysis to remove the sulphate groups they were identified as (20R)-24-methylenecholestane-3β,21-diol (3a) (major), (20R)-24-methylenecholest-5-ene-3β,21-diol (3b) (minor), (20R,22E)-methylcholest-22-ene-3β,21-diol (4a) (major), (20R)-cholestane-3β,21-diol (1a) (minor), (20R,22E)-cholest-22-ene-3β,21-diol (2a) (minor), and (20R)-cholest-5-ene-3β,21-diol (1b) (minor).The less polar compouds are sterol sulphates wich are "normal" constituents of starfishes.Analysis of the free sterols mixture has revealed that it contains a low level of cholest-7-en-3β-ol (3percent of the total sterol mixtures) and C26, C27, C28, and C29 5α-steroidal alcohols.This finding, in contrast with previous results indicating the preponderance of Δ7-sterols in starfishes, could be related to the apparent absence of asterosaponins in this species.