487029-68-5

Basic information

• Product Name: R- 4-(1-Methylethyl)-3-(1-oxopropyl)-2-Thiazolidinethione
• Synonyms: R- 4-(1-Methylethyl)-3-(1-oxopropyl)-2-Thiazolidinethione;(R)-4-Isopropyl-3-(1-oxopropyl)-2-thiazolidinethione,99%e.e.;(R)-4-Isopropyl-3-(1-oxopropyl)-2-thiazolidinethione
• CAS NO: 487029-68-5
• Molecular Formula: C9H15NOS2
• Molecular Weight: 217.3515
• Mol File: 487029-68-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: R- 4-(1-Methylethyl)-3-(1-oxopropyl)-2-Thiazolidinethione(CAS DataBase Reference)
• NIST Chemistry Reference: R- 4-(1-Methylethyl)-3-(1-oxopropyl)-2-Thiazolidinethione(487029-68-5)
• EPA Substance Registry System: R- 4-(1-Methylethyl)-3-(1-oxopropyl)-2-Thiazolidinethione(487029-68-5)

Safety Data

• Hazardous Substances Data: 487029-68-5(Hazardous Substances Data)

Upstream product

• 2026-48-4 (S)-valinol 
• 110199-16-1 4(R)-isopropyl-1,3-thiazolidine-2-thione 
• 79-03-8 propionyl chloride 
• 4276-09-9 (R)-2-amino-3-methylbutanol 
• 1293368-27-0 D-valine 
• 640-68-6 D-Val-OH 
• 123-62-6 propionic acid anhydride 
• 76186-04-4 (S)-4-isopropylthiazolidine-2-thione 
• 802294-64-0 propionic acid 

Downstream Products

• 76186-04-4 (S)-4-isopropylthiazolidine-2-thione 

Relevant articles and documents

A acylation of the synthesis method of sulfur on behalf of the oxazolidone

The invention discloses a method for acylation of the synthesis method of sulfur on behalf of the oxazolidone. Synthesis method of the invention, comprising the following steps: in the non-protic organic solvent, the compound III and under the action of a

Synthesis and Fungicidal Activity of Simple Structural 1,3-Thiazolidine-2-Thione Derivatives

A series of simple structural 1,3-thiazolidine-2-thione derivatives with various substituents on the S-, N-, 4-, and 5-positions was synthesized with high yields from various vicinal amino alcohols via two steps and screened for their antifungal activity. Bioassay results reveal that some thiazolidine-2-thione derivatives show strong antifungal activities against P. capsici, G. zeae, S. sclerotiorum, A. alternata, B. cinerea, or R. solani. The SAR analysis indicates that N-acyl substituted and 4-alkyl substituents can enhance the antifungal activity. Notably, 4-isopropyl-N-propionylthiazoldine-2-thione shows excellent activity against B. cinerea and G. zeae with IC50 values at 3.7 g/mL and 6.5 g/mL, respectively, and 4-isobutyl-N-propionylthiazoldine-2-thione shows remarkable fungicidal activity against R. solani, S. sclerotiorum, and G. zeae with IC50 values at 1.0 g/mL, 12.1 g/mL, and 11.0 g/mL, respectively. GRAPHICAL ABSTRACT.

Absolute configuration of lactams and oxazolidinones using kinetic resolution catalysts

A simple method for determining the absolute configuration of oxazolidinones, lactams, and their derivatives using kinetic resolution catalysts is described. The optically pure substrates were acylated using the (S)-HBTM and the (R)-HBTM catalyst, and the faster reaction was determined. An empirical mnemonic was developed for the assignment of the absolute configuration based on the fast-reacting catalyst.