49597-17-3

Basic information

• Product Name: 5-OXO-1-PHENYL-2,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXYLIC ACID
• Synonyms: 5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxylic acid(SALTDATA: FREE)
• CAS NO: 49597-17-3
• Molecular Formula: C₁₀H₈N₂O₃
• Molecular Weight: 204.19
• Mol File: 49597-17-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 358.775°C at 760 mmHg
• Flash Point: 170.782°C
• Appearance: /
• Density: 1.458g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 5-OXO-1-PHENYL-2,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-OXO-1-PHENYL-2,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(49597-17-3)
• EPA Substance Registry System: 5-OXO-1-PHENYL-2,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(49597-17-3)

Safety Data

• Hazardous Substances Data: 49597-17-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H8N2O3/c13-9-6-8(10(14)15)11-12(9)7-4-2-1-3-5-7/h1-6,11H,(H,14,15)

Upstream product

• 110-86-1 pyridine 
• 7459-46-3 triethyl 1,1,2-ethanetricarboxylate 
• 100-34-5 benzene diazonium chloride 
• 10359-15-6 diethyl 2-cyanosuccinate 
• 59-88-1 phenylhydrazine hydrochloride 
• 6153-53-3 Oxalacetic acid enolate 
• 100-63-0 phenylhydrazine 
• 142-45-0 Acetylenedicarboxylic acid 
• 46730-12-5 ketomalonic acid phenylhydrazone 
• 22158-22-1 phenylhydrazono-succinic acid dimethyl ester 
• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 
• 7732-18-5 water 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 

Downstream Products

• 1297537-53-1 N-(2-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)ethyl)-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxamide 
• 28710-96-5 5-oxo-1-phenyl-2,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 7456-81-7 2-phenyl-1,2-dihydro-pyrazol-3-one 
• 41405-77-0 1-Phenyl-2-methyl-5-pyrazolon-3-carbonsaeure 

Relevant articles and documents

ANDROGEN RECEPTOR MODULATING COMPOUNDS

Compounds of formula (I) wherein R1 to R16, A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

Process for the manufacture of pyrazolones from pyrazolidones

A process for manufacture of pyrazolones of the formula: STR1 wherein R is an aromatic radical and R1 is an alkyl, carboxylic acid, carbamoyl or carboxylic ester group which comprises treating a pyrazolidone of the formula: STR2 wherein R and R