49615-87-4

Upstream product

• 99-90-1 para-bromoacetophenone 
• 110-46-3 isopentyl nitrite 
• 71559-14-3 2-azido-1-(4-bromophenyl)ethanone 
• 126629-81-0 methyl 3-(4-bromophenyl)-3-oxopropanoate 

Downstream Products

• 86435-90-7 (4-bromo-phenyl)-glyoxal dioxime 
• 41147-82-4 4-Bromophenylethanolamine 
• 80352-42-7 1-(4-bromophenyl)-2,2-dihydroxyethanone 
• 5467-72-1 α-amino-4-bromoacetophenone hydrochloride 
• 77851-92-4 Cu(p-BrC₆H₄COCHNO)2 
• 49615-71-6 4-(4-bromophenyl)-1,2,5-oxadiazol-3-amine 

Relevant academic research and scientific papers

Site-selective conversion of azido groups at carbonyl α-positions into oxime groups leading triazide to a triple click conjugation scaffold

This paper reports the selective conversion of alkyl azido groups at the carbonyl α-position into oximes through β-elimination of dinitrogen, followed by transoximation. With this method and diazo conversion, a triazido molecule was transformed into a triple click conjugation scaffold allowing one-pot four-component coupling.

One-pot synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans

A "one pot" method for the synthesis of 3-amino-4-aryl- and 3-amino-4-hetarylfurazans from β-aryl- and 4-β-hetaryl-β-oxo acid esters was developed.