4964-49-2

Usage

Uses

Used in Organic Synthesis:
1-(2-Aminophenyl)ethan-1-one oxime is used as a reagent for the preparation of various organic compounds. Its unique structure allows for versatile reactions and the formation of a wide range of products, making it a valuable tool in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(2-Aminophenyl)ethan-1-one oxime is used as a building block in the synthesis of pharmaceutical drugs and other biologically active compounds. Its structural properties enable the development of new drug candidates with potential therapeutic applications.
Used in Drug Discovery:
1-(2-Aminophenyl)ethan-1-one oxime has been investigated for its potential use in the development of new drugs and therapies for various medical conditions. Its unique chemical properties and reactivity make it a promising candidate for the creation of novel therapeutic agents.
Overall, 1-(2-Aminophenyl)ethan-1-one oxime is a versatile and important compound in the fields of organic chemistry, pharmaceutical research, and drug discovery, with applications in the synthesis of organic compounds, development of pharmaceutical drugs, and exploration of new therapeutic agents for various medical conditions.

Upstream product

• 551-93-9 2-aminoacetophenone 
• 25384-14-9 2-aminoacetophenone hydrochloride 
• 7647-01-0 hydrogenchloride 
• 5653-21-4 metazonic acid 
• 7732-18-5 water 
• 41608-06-4 4-methyl-1,2,3-benzotriazine 3-oxide 
• 7803-49-8 hydroxylamine 
• 141-52-6 sodium ethanolate 

Downstream Products

• 39909-26-7 2-(1-aminoethyl)aniline 
• 1742-21-8 4-Methyl-2-(3-nitrophenyl)-1,2-dihydrochinazolin-3-oxid 
• 1742-19-4 1,2-dihydro-4-methyl-2-phenylquinazoline 3-oxide 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 3176-62-3 3-methyl-1H-indazole 
• 84904-42-7 o-(phenylazo)acetophenone oxime 
• 1239313-33-7 2'-(benzylideneamino)acetophenone oxime 
• 551-93-9 2-aminoacetophenone 
• 1640-57-9 2-(2-hydroxyphenyl)-4-methyl-1,2-dihydroquinazoline-3-oxide 
• 1806-59-3 4-methyl-2-phenylquinazoline 3-oxide 
• 1585235-42-2 2-benzyl-4-methylquinazoline 3-oxide 

Relevant academic research and scientific papers

Preparation, characterization and biological activity of new tridentate imine-oxime ligand (H2L) and Its metal complexes

The new tridentate Schiff-oxime ligand 1-[2-(2,4-dihydroxybenzylidene)aminophenyl]ethanone oxime (H2L), prepared via condensation of equal amounts of 1-(2-aminophenyl)ethanone oxime and 4-hydroxysalicylaldehyde. H2L ligand characterized by using FTIR, UV-

Eco-friendly H2O2 oxidation of 1,2-dihydroquinazoline-3-oxides to quinazoline-3-oxides

2-Aminobenzaldehyde, 1-(2-aminophenyl)ethanone, and 2-aminophenyl phenyl methanone oximes 1 were reacted with aromatic aldehydes to give the corresponding 1,2-dihydroquinazoline-3-oxides 2. The latter were converted in high yields to a series of quinazoli

A convenient approach to 2,4-disubstituted quinazoline-3-oxides using active MnO2 as the oxidant

Using cheap, readily available, and economic active MnO2 as an oxidant, a series of 2,4-disubstituted quinazoline-3-oxides were synthesized in good to excellent yields by oxidation of the corresponding 1,2-dihydroquinazoline-3-oxides under mild

A advantage Ralli sandbank intermediate and its preparation method and application

The present invention relates to a linagliptin intermediate, a preparation method and applications thereof, wherein the linagliptin intermediate has the structure represented by general formulas (II) and (IV), and X is halogen. According to the present invention, the compound of the present invention is the solid and has characteristics of low production cost, easy purification and easy storage, linagliptin can be efficiently prepared, and the method is suitable for industrial scale production.

Visible light-mediated synthesis of quinazolines from 1,2- dihydroquinazoline 3-oxides

A series of quinazolines were synthesized in good to excellent yields by exposing 1,2-dihydroquinazoline 3-oxides to visible light in acetonitrile without the presence of any external sensitizers. The only exception was the 2-(p-nitrophenyl)-substituted s

METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS

A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles.

An efficient synthesis of quinazolines: a theoretical and experimental study on the photochemistry of oxime derivatives

A new photochemical method for the preparation of quinazolines (2) through irradiation of [2-(methyleneamino)phenyl]methanone oximes (1) is reported. The photoreaction has been studied in depth by experimental, theoretical and photochemical methods. A six-electron electrocyclic ring closure mechanism, followed by water loss, is proposed and rationalized to explain the formation of quinazolines (2).

A practical, metal-free synthesis of 1H-Lndazoles

The synthesis of 1H-indazoles is achieved from o-aminobenzoximes by the selective activation of the oxime in the presence of the amino group. The reaction occurs with a variety of substituted o-aminobenzoximes using a slight excess of methanesulfonyl chloride and triethylamine at 0-23 °C and is amenable to scale-up. The synthesis of 1 H-indazoles under these conditions is extremely mild compared with previous synthetic approaches and affords the desired compounds in good to excellent yields.

Mechanism of selective formation of 2-amino-substituted 1,4-benzodiazepin-4-oxides and 2-aminomethyl substituted quinazolin-3-oxides from chloromethyl quinazolin-N-oxides indications from perturbation theory

The o-amino-acetophenone and -benzophenone oximes 1a-c react with chloroacetyl chloride giving the 2-chloromethyl-quinazoline-3-oxides 6a-c. The mechanism is explained using the perturbation theory. With ammonia and N-prim. aliphatic amines, compounds 6a-c yield 1,4-benzodiazepines 16 and 17 as ring-enlarged products, with aromatic and with N-sec. aliphatic amines, quinazoline derivatives 10-13 are formed. The constitution of the heterocycles is proved by nmr spectroscopic methods. Selective formation of the heterocyclic products is explained with the relative thermodynamic stability of the corresponding 2-adducts 14.

Algicidal and fungicidal 2-haloalkyl-3-oxo-4-substituted quinazoline

2-Haloalkyl-3-oxo-4-substituted quinazolines represented by the formula STR1 wherein R is hydrogen, lower alkyl, lower alkyl substituted with one to three of the same or different halogens, phenyl or phenyl substituted with 1 to 3 of the same or different