51028-38-7Relevant articles and documents
Single-triggered trimeric prodrugs
Haba, Keren,Popkov, Mikhail,Shamis, Marina,Lerner, Richard A.,Barbas, Carlos F.,Shabat, Doron
, p. 717 - 720 (2007/10/03)
The knock-on effect of a single catalytic reaction by a specific enzyme on a prodrug platform initiates the sequential collapse of the whole array to release the active drug units (see scheme). Such a dendritic system may provide a means to improve select