51094-24-7

Upstream product

• 124-38-9 carbon dioxide 
• 593-51-1 methylamine hydrochloride 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 1000-70-0 bis(trimethylsilyl)carbodi-imide 
• 74-89-5 methylamine 
• 58078-34-5 trimethylsilyl carbamate 
• 75-77-4 chloro-trimethyl-silane 
• 65398-48-3 methylammonium N-methylcarbamate 
• 16513-17-0 methyltrimethylsilylamine 

Downstream Products

• 6838-45-5 1,1,3,3-tetrachloro-1,3-diphenyldisiloxane 
• 22858-38-4 1,3,5-Triphenyl-pentachlor-trisiloxan 
• 22858-39-5 1,3,5,7-Tetraphenyl-hexachlor-tetrasiloxan 
• 31675-59-9 trimethylsilyl bis(chloromethyl)phosphinate 
• 624-83-9 methyl isocyanate 
• 27445-88-1 tetrakis(chloromethyl)pyrophosphinate 

Relevant academic research and scientific papers

Organosilicon synthesis of isocyanates: II. Synthesis of aliphatic, carbocyclic, and fatty-aromatic isocyanates

Silylation of a series of aliphatic, carbocyclic, and fatty-aromatic amines gave the corresponding silyl derivatives whose yield depended on the electronic and steric structure of the substrate and the nature of the silylating agent. The yield of isocyanates obtained by phosgenation of the silyl derivatives under mild conditions decreased in going from aliphatic amines to benzylamines and rose as the length of the alkyl chain in fatty-aromatic amines extended. The most convenient procedure for the synthesis of low-boiling alkyl isocyanates was found to be based on the transformation of amines or ammonium salts into silyl or silyl silyl-carabamates, followed by pyrolysis of the latter in the presence of trichloro(phenyl)silane. Pleiades Publishing, Inc., 2006.

TRIMETHYLSILYLATED N-ALKYL-SUBSTITUTED CARBAMATES. I. PREPARATION AND SOME REACTIONS

Trimethylsilyl N-monoalkyl- and N,N-dialkyl-carbamates have been made in 85-95percent yields by silylation of the corresponding ammonium carbamates with trimethylchlorosilane.Trimethylsilyl N,N-dimethylcarbamate can be used for silylation of alcohols, phenols, and carboxylic acids.The silylcarbamates react with carboxylic acid halides to give the corresponding acid amides.The reaction of trimethylsilyl carbamates with carboxylic anhydrides give the corresponding silyl carboxylate and acid amide, while the reaction with dicarboxylic anhydrides give the trimethylsilyl monoamide of the corresponding dicarboxylic acid, i.e.Me3SiO2CCONR1R2.