65398-48-3

Basic information

• Product Name: methylcarbamic acid - methanamine (1:1)
• CAS NO: 65398-48-3
• Molecular Formula: CH₅N*C₂H₅NO₂
• Molecular Weight: 106.1237
• Mol File: 65398-48-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 206.5°C at 760 mmHg
• Flash Point: 78.7°C
• Vapor Pressure: 0.0959mmHg at 25°C
• CAS DataBase Reference: methylcarbamic acid - methanamine (1:1)(CAS DataBase Reference)
• NIST Chemistry Reference: methylcarbamic acid - methanamine (1:1)(65398-48-3)
• EPA Substance Registry System: methylcarbamic acid - methanamine (1:1)(65398-48-3)

Safety Data

• Hazardous Substances Data: 65398-48-3(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 74-89-5 methylamine 
• 15719-64-9 methylammonium carbonate 

Downstream Products

• 124-38-9 carbon dioxide 
• 74-89-5 methylamine 
• 622-29-7 N-Benzylidenemethylamine 
• 1125-90-2 1-(2-methoxyphenyl)-N-methylmethanimine 
• 13114-22-2 N-(4-chlorobenzylidene)methylamine 
• 35003-56-6 1-(4-bromophenyl)-N-methylmethanimine 
• 121004-44-2 N-methyl-1-(3-nitrophenyl)methanimine 
• 3117-65-5 2-(methyliminomethyl)phenol 
• 72037-46-8 1-methyl-4-phenyl-1-azabutadiene 
• 51094-24-7 trimethylsilyl N-methylcarbamate 
• 96-31-1 N,N'-Dimethylurea 

Relevant articles and documents

Stable carbamate pathway towards organic-inorganic hybrid perovskites and aromatic imines

Methyl ammonium methyl carbamate (MAC), formulated as CH3NH3+CH3NHCO2-, was synthesized by reacting liquid methylamine with supercritical CO2, and its structure was refined by single-crystal X-ray diffraction. MAC is a white crystalline salt and is as reactive as methylamine, and is a very efficient alternative to toxic methylamine. We were able to produce hybrid perovskite MAPbI3 (MA = methyl ammonium) by grinding MAC with PbI2 and I2 at room temperature, followed by storing the mixed powder. Moreover, this one-pot method is easily scalable for the large-scale synthesis of MAPbI3 in a small vessel. We have also investigated the reactivity of MAC towards aromatic aldehydes in the absence of solvent. The solventless reactions afforded imines as exclusive products with over 97% yield, which show higher selectivity than the methylamine-based synthesis. Complete conversions were typically accomplished within 3 h at 25 °C. The results of this study emphasize the importance of solid carbamates such as MAC to develop an environmentally friendly process for the synthesis of various amine-based materials on the industrial scale.

Organocatalytic knoevenagel condensations by means of carbamic acid ammonium salts

The Knoevenagel condensation between an active methylene compound and an aromatic aldehyde with a carbamic acid ammonium salt used as an organocatalyst gave the desired Knoevenagel products in up to 98% yield. The reaction occurred at rt and in a short reaction time under solvent-free conditions. In addition, no extraction, wash, or chromatography steps were needed to obtain a high-purity Knoevenagel product.