51209-80-4Relevant articles and documents
Enantiotopic Discrimination by Coordination-Desymmetrized meso-Ligands
Li, Yutang,Lidskog, Anna,Armengol-Relats, Helena,Pham, Thanh Huong,Favraud, Antoine,Nicolas, Maxime,Dawaigher, Sami,Xiao, Zeyun,Ma, Dayou,Lindb?ck, Emil,Strand, Daniel,W?rnmark, Kenneth
, p. 1575 - 1579 (2020/02/04)
The first examples of enantiopure catalysts that are chiral merely due to coordination of different metal ions at enantiotopic positions of an achiral meso-ligand are reported. These catalysts exhibit a pseudo-Cs symmetry and are able to catalyze reactions demanding simultaneous involvement of two catalytic sites. The latter was demonstrated by application in the asymmetric ring-opening of meso-epoxides.
1,2-Ferrocenediylazaphosphinines 2: A new class of nucleophilic catalysts for ring-opening of epoxides
Paek, Seung Hwan,Shim, Sang Chul,Cho, Chan Sik,Kim, Tae-Jeong
, p. 849 - 851 (2007/10/03)
1,2-Ferrocenediylazaphosphinines (1a-c) have been successfully employed as a new class of nucleophilic catalysts for ring-opening of a range of epoxides, their catalytic efficiency in terms of regioselectivity as well as chemical yield comparing well with the existing catalysts in the literature. In contrast, low enantiomeric excesses have been obtained from the reactions of meso-epoxides catalyzed by (R)-1.
Facile O-silylation of tertiary alcohols in the presence of Mg-metal
Nishiguchi, Ikuzo,Kita, Yoshio,Watanabe, Masamitsu,Ishino, Yoshio,Ohno, Toshinobu,Maekawa, Hirofumi
, p. 1025 - 1027 (2007/10/03)
Treatment of aliphatic alcohols with trimethylsilyl chloride (TMSCl) in N,N-dimethylformamide (DMF) containing Mg-turning at room temperature brought about facile and efficient O-silylation to give the corresponding trimethylsilyl ethers in good to excellent yields. This method can be also available for sterically hindered tert-alcohols and alcohols having a variety of substituents which may be labile under the basic conditions used in the conventional O-silylation.
