51231-11-9Relevant academic research and scientific papers
Synthesis and Antiproliferative Activity of Nitric Oxide-Donor Largazole Prodrugs
Borgini, Matteo,Botta, Maurizio,Fabio, Romano Di,Ferrante, Luca,Poggialini, Federica,Summa, Vincenzo,Zamperini, Claudio
, p. 846 - 851 (2020)
The marine natural product Largazole is the most potent Class I HDAC inhibitor identified to date. Since its discovery, many research groups have been attracted by the structural complexity and the peculiar anticancer activity, due to its capability to di
Olefins from biomass feedstocks: Catalytic ester decarbonylation and tandem Heck-type coupling
John, Alex,Hogan, Levi T.,Hillmyer, Marc A.,Tolman, William B.
supporting information, p. 2731 - 2733 (2015/03/05)
With the goal of avoiding the need for anhydride additives, the catalytic decarbonylation of p-nitrophenylesters of aliphatic carboxylic acids to their corresponding olefins, including commodity monomers like styrene and acrylates, has been developed. The reaction is catalyzed by palladium complexes in the absence of added ligands and is promoted by alkali/alkaline-earth metal halides. Combination of catalytic decarbonylation and Heck-type coupling with aryl esters in a single pot process demonstrates the viability of employing a carboxylic acid as a "masked olefin" in synthetic processes. This journal is
Syntheses and characterisation of novel cyclodextrin vinyl derivatives from cyclodextrin-nitrophenol-derivatives
Nielsen, Anne L.,Steffensen, Kim,Wimmer, Reinhard,Worm-Leonhard, Martin,Larsen, Kim L.
experimental part, p. 303 - 315 (2011/11/29)
In this study novel reactive α-, β- and γ-cyclodextrin-esters (acrylate, pent-4-enoate and undec-10-enoate) have been synthesised and characterised. The syntheses were carried out by using nitrophenol-esters with the ability to form inclusion complexes wi
