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(4-methylphenylthio)methyl methyl ether, also known as 4-methylphenyl methyl sulfide methyl ether, is an organic compound with the chemical formula C9H12OS. It is a colorless liquid that is soluble in organic solvents and has a molecular weight of 164.26 g/mol. (4-methylphenylthio)methyl methyl ether is characterized by the presence of a methyl group (-CH3) attached to a phenyl ring, which is further connected to a sulfur atom (S), forming a phenylthio group. The sulfur atom is bonded to a methylene group (-CH2-), which is then connected to a methoxy group (-OCH3). This structure endows the compound with unique chemical properties, making it a potential intermediate in the synthesis of various organic compounds and pharmaceuticals. It is important to handle (4-methylphenylthio)methyl methyl ether with care due to its potential reactivity and sensitivity to air and moisture.

51290-72-3

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51290-72-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 51290-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,9 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 51290-72:
(7*5)+(6*1)+(5*2)+(4*9)+(3*0)+(2*7)+(1*2)=103
103 % 10 = 3
So 51290-72-3 is a valid CAS Registry Number.

51290-72-3Relevant academic research and scientific papers

Electrochemical Oxidation Enables Regioselective and Scalable α-C(sp3)-H Acyloxylation of Sulfides

Wang, Huamin,He, Meng,Li, Yongli,Zhang, Heng,Yang, Dali,Nagasaka, Masanari,Lv, Zongchao,Guan, Zhipeng,Cao, Yangmin,Gong, Fengping,Zhou, Zhilin,Zhu, Jingyun,Samanta, Supravat,Chowdhury, Abhishek Dutta,Lei, Aiwen

supporting information, p. 3628 - 3637 (2021/04/07)

A highly selective, environmentally friendly, and scalable electrochemical protocol for the construction of α-acyloxy sulfides, through the synergistic effect of self-assembly-induced C(sp3)-H/O-H cross-coupling, is reported. It features exceptionally broad substrate scope, high regioselectivity, gram-scale synthesis, construction of complex molecules, and applicability to a variety of nucleophiles. Moreover, the soft X-ray absorption technique and a series of control experiments have been utilized to demonstrate the pivotal role of the self-assembly of the substrates, which indeed is responsible for the excellent compatibility and precise control of high regioselectivity in our electrochemical protocol.

P4VPy–CuO nanoparticles as a novel and reusable catalyst: application at the protection of alcohols, phenols and amines

Shirini, Farhad,Fallah-Shojaei, Abdollah,Abedini, Masoumeh,Samavi, Laleh

, p. 1699 - 1712 (2016/07/27)

P4VPy–CuO nanoparticles were synthesized using ultrasound irradiations. Relevant properties of the synthesized nanoparticles were investigated by X-ray diffraction, scanning electron microscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. After identification, the prepared reagent was used for the promotion of different types of protection reactions of alcohols, phenols and amines. Easy workup, short reaction times, excellent yields, relatively low cost and reusability of the catalyst are the striking features of the reported methods.

Gold-Catalyzed, Iodine(III)-Mediated Direct Acyloxylation of the Unactivated C(sp3)–H Bonds of Methyl Sulfides

Guo, Sheng-rong,Santhosh Kumar, Pailla,Yuan, Yan-qin,Yang, Ming-hua

, p. 4260 - 4264 (2016/09/14)

The gold-catalyzed, iodine(III)-mediated direct oxidative acyloxylation of the C(sp3)–H bonds of methyl sulfides for the synthesis of various α-thioaryl and α-thioalkyl ester derivatives was discovered. Bis(acyloxy)iodobenzene proved to be an efficient reagent to activate the sulfur atom as an in situ directing group for α-C(sp3)–H functionalization. The attractive features of this protocol include short reaction times, low catalyst loading, and in situ activation of adjacent C(sp3)–H bonds of the sulfur atom.

A novel approach to the practical synthesis of sulfides: An InBr 3-Et3SiH catalytic system promoted the direct reductive sulfidation of acetais with disulfides

Sakai, Norio,Moritaka, Kohei,Konakahara, Takeo

supporting information; experimental part, p. 4123 - 4127 (2009/12/09)

We have demonstrated a facile and direct synthesis of sulfide derivatives using acetais and ketals, derived, from aromatic/ conjugated, aldehydes and aromatic ketones, with disulfides and the InBr3-Et3SiH reducing system., We also succeeded in developing an unprecedented one-pot preparation of an aliphatic sulfide from a disulfide and an aliphatic acetal. (Wiley-VCH Verlag GmbH & Co. KGaA.

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