5131-59-9

Basic information

• Product Name: 2,4,8-trichlorophenanthridin-6(5H)-one
• CAS NO: 5131-59-9
• Molecular Formula: C₁₄H₁₀N₄O₆
• Molecular Weight: 298.5518
• Mol File: 5131-59-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 368.7°C at 760 mmHg
• Flash Point: 176.8°C
• Density: 1.535g/cm³
• Vapor Pressure: 1.25E-05mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 2,4,8-trichlorophenanthridin-6(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,8-trichlorophenanthridin-6(5H)-one(5131-59-9)
• EPA Substance Registry System: 2,4,8-trichlorophenanthridin-6(5H)-one(5131-59-9)

Safety Data

• Hazardous Substances Data: 5131-59-9(Hazardous Substances Data)

Usage

General Description

2,4,8-trichlorophenanthridin-6(5H)-one is a synthetic chemical compound that belongs to the class of phenanthridine alkaloids. It is a tricyclic heterocyclic compound with a phenanthridine skeleton and three chlorine atoms attached to the 2nd, 4th, and 8th positions. 2,4,8-trichlorophenanthridin-6(5H)-one has been studied for its potential pharmacological activities, including its ability to inhibit DNA topoisomerase I and its antitumor properties. It has also been investigated for its antimicrobial and antifungal properties. Additionally, 2,4,8-trichlorophenanthridin-6(5H)-one has been studied for its role as a photosensitizer in photodynamic therapy for cancer treatment. However, further research is needed to fully understand the potential uses and effects of this chemical compound.

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Relevant articles and documents

Fine tuning of receptor polarity for the development of selective naked eye anion receptor

We designed and synthesized new anion receptors 1, 2, and 3, which have different N-H polarity. According to their N-H polarities, these receptors showed different selectivities for the anions they were interacting with. The difference of selectivity coul

Heterocycles from Heterocycles. 1,3-Diaryl-4,5-imidazolidinediones from 1,3,5-Triarylhexahydro-1,3,5-triazines and Oxalyl Chloride

1,3-Diaryl-4,5-imidazolidinediones (6) are easily synthesized from 1,3,5-triarylhexahydro-1,3,5-triazines (1) and oxalyl chloride (5) in a reaction not likely to involve the zwitterionic intermediate (3) of the N-methylenearylamine dimer, but viewing the sequential pick up of two units of the monomer (2) by oxalyl chloride (5).The essential role of ethyl alcohol added to the reaction mixture is recognized.Reaction conditions have been optimized and some ten imidazolidinediones (6) were prepared in good to excellent yields.Geometric parameters of 6 were obtained by X-ray diffraction analysis: all the nuclei are found almost in one plane except for a small twist of the phenyl rings about the C-N bond.