5132-17-2

Upstream product

• 625-77-4 N-acetylacetamide 
• 540-23-8 p-toluidine hydrochloride 
• 16900-53-1 3-bromopropiolic acid 
• 106-49-0 p-toluidine 
• 64-19-7 acetic acid 
• 598-72-1 2-Bromopropionic acid 
• 103-89-9 4-Methylacetanilide 
• 927-80-0 1-ethoxyacetylene 
• 75-44-5 phosgene 
• 98-95-3 nitrobenzene 
• 75-05-8 acetonitrile 
• 125781-67-1 1--1H-benzotriazole 
• 78-39-7 Triethyl orthoacetate 
• 32324-09-7 N¹-benzoyl-N¹,N²-bis(p-methylphenyl)acetamidine 

Downstream Products

• 22316-59-2 2-methyl-3-p-tolyl-4(3H)-quinazolinone 
• 128799-73-5 N¹-(p-Chlorobenzoyl)-N¹,N²-di-p-tolyl-acetamidine 
• 106210-29-1 bis-(N,N'-di-p-tolylacetamidino)palladium(II) 
• 90527-02-9 (Re(CO)4(CH₃C₆H₄NHC(CH₃)NC₆H₄CH₃)Br) 
• 51446-58-3 mer,trans-BrRe(CO)3(PPh₃)2 
• 680224-03-7 [Mo(η(3)-allyl)Cl(CO)2(N,N'-di(p-tolyl)acetamidine))2] 
• 186193-74-8 [Pd2Cl2(μ-4-CH3C6H4NC(Me)CNC6H4-4-CH3)2(PBu3)2] 
• 32324-09-7 N¹-benzoyl-N¹,N²-bis(p-methylphenyl)acetamidine 
• 89523-42-2 1,1-bisethene 
• 27535-88-2 2,6-dimethyl-1-(4-methylphenyl)-1H-benzo[d]imidazole 
• 129957-33-1 N¹-Tosyl-N¹-(p-methoxyphenyl)-N²-(p-methylphenyl)acetamidine 
• 129957-36-4 N¹-(p-Nitrophenyl)-N¹,N²-di(p-methylphenyl)acetamidine 
• 129957-34-2 N¹-(p-Nitrobenzenesulfonyl)-N¹,N²-di(p-methylphenyl)acetamidine 
• 129957-31-9 N¹-(m-Nitrobenzenesulfonyl)-N¹,N²-di-(p-methoxyphenyl)acetamidine 

Relevant academic research and scientific papers

Microwave-assisted synthesis of N,N′-disubstituted acetamidine ligands

Under microwave activation, triethylorthoacetate reacts with the substituted anilines in the presence of acetic acid as a catalyst, producing acetamidine in moderate to high yields. The X-ray structures of the new amidines, N,N′-bis(3,5-dimethylphenyl)-ac

Efficient microwave access to polysubstituted amidines from imidoylbenzotriazoles

Microwave reactions of primary and secondary amines with imidoylbenzotriazoles 6a-w gave diversely substituted amidines 7a-Aa in 76-94% yields. Convenient preparations of a variety of amides 5a-Ab (87-96%) and imidoylbenzotriazoles 6a-w (56-95%) have also been developed using microwave irradiation under mild conditions and short reaction times. These results demonstrate further the advantages of microwave synthesis and introduce a new application of imidoylbenzotriazoles in the preparation of polysubstituted amidines.

Hydrolysis of Acyl Derivatives of N1,N2-Diarylamidine. I

The alkaline hydrolyses of N1-benzoyl-N1,N2-diarylacetamidine (V) and N1-tosyl-N1,N2-diarylacetamidine (IX) were examined.In the hydrolysis of V, hydroxide ion attacked the amide carbonyl carbon to form N1,N2-diarylacetamidine and benzoic acid.In the hydrolysis of IX, hydroxide ion attacked the amidine carbon, and elimination of the N-tosylarylamino group and arylimino group proceeded in parallel, with that of the latter predominating.The alcoholysis reaction of V proceeded without any added catalyst, in contrast to the case of 1-(N-benzoylarylamino)-3-arylimino-1-propene.A unique peak corresponding to the loss of 64 mass units (sulfur dioxide) was observed in the mass spectrum of IX.Keywords - alkaline hydrolysis; alcoholysis; N1-benzoyl-N1,N2-diarylacetamidine; N1-tosyl-N1,N2-diarylacetamidine; 1,1-bis(N-benzoylarylamino)ethene; MS

Catalytic and Non-catalytic Addition of Aromatic Amines to Terminal Acetylenes in the Presence of Mercury(II) Chloride and Acetate

The addition of aromatic amines to terminal acetylenes in the presence of catalytic amounts of mercury(II) chloride gives imines, enamines, and 1,2,3,4-tetrahydroquinoline derivatives; mercury(II) acetate shows considerably less catalytic activity and may be used for the non-catalytic preparation of imines, enamines, N,N'-disubstituted acetamidines, and N,N-disubstituted acetamides.