5176-14-7

Basic information

• Product Name: 3-Phenyl-2,1-benzisoxazole
• Synonyms: 3-Phenyl-2,1-benzisoxazole
• CAS NO: 5176-14-7
• Molecular Formula: C₁₃H₉NO
• Molecular Weight: 195.22
• Mol File: 5176-14-7.mol
• Article Data: 23

Chemical Properties

• Melting Point: 83 °C
• Boiling Point: 363.5±11.0 °C(Predicted)
• Appearance: /
• Density: 1.184±0.06 g/cm3(Predicted)
• PKA: -3.02±0.30(Predicted)
• CAS DataBase Reference: 3-Phenyl-2,1-benzisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenyl-2,1-benzisoxazole(5176-14-7)
• EPA Substance Registry System: 3-Phenyl-2,1-benzisoxazole(5176-14-7)

Safety Data

• Hazardous Substances Data: 5176-14-7(Hazardous Substances Data)

Upstream product

• 2243-79-0 2-nitrobenzophenone 
• 5840-40-4 2-nitrodiphenylmethane 
• 63645-25-0 α-(2-nitrophenyl)deoxybenzoin 
• 140-29-4 phenylacetonitrile 
• 98-95-3 nitrobenzene 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 100-42-5 styrene 
• 108-88-3 toluene 
• 16714-27-5 (2-azidophenyl)(phenyl)methanone 
• 36367-99-4 2-Diazobenzophenon-Kation 
• 71-43-2 benzene 
• 612-23-7 2-nitrobenzyl chloride 
• 91-17-8 decalin 
• 552-89-6 2-nitro-benzaldehyde 

Downstream Products

• 5621-66-9 [2-amino-3-chlorophenyl]phenylmethanone 
• 69751-74-2 (2-amino-3,5-dibromophenyl)phenylmethanone 
• 1039-51-6 2,4-diphenylquinoline 
• 1721-92-2 2-methyl-4-phenylquinoline 
• 129190-65-4 11-phenylbenzofuro<2,3-b>quinoline 
• 23592-61-2 [2‐[(4‐methylphenyl)amino]phenyl](phenyl)methanone 
• 73968-17-9 phenyl(2-((1-phenylethyl)amino)phenyl)methanone 
• 10380-73-1 2,3,4-triphenyl quinoline 
• 109271-64-9 phenyl(4-phenylquinazolin-2-yl)methanone 
• 10265-83-5 9-phenyl-1,2,3,4-tetrahydroacridine 

Relevant articles and documents

Metal-Free [3+2] Annulation of Ynamides with Anthranils to Construct 2-Aminoindoles

A novel metal-free [3+2] annulation of ynamides with anthranils provides a facile, flexible, environmentally friendly, and atom-economical route to 2-aminoindoles. This synthetic process proceeds with efficiency, excellent regioselectivity, and wide functional group tolerance under mild conditions. Moreover, the obtained 2-aminoindole products represent a multifunctional platform for the construction of various 2-aminoindolyl frameworks.

TfOH-Promoted Decyanative Cyclization toward the Synthesis of 2,1-Benzisoxazoles

A novel solvent-free, TfOH-promoted decyanative cyclization approach for the synthesis of 2,1-benzisoxazoles has been developed. The reactions are complete instantly at room temperature and result in the formation of the desired 2,1-benzisoxazoles in a 34-97% isolated yield.

Metal-Free, Visible-Light-Enabled Direct C3-H Arylation of Anthranils

An eosin Y disodium salt-catalyzed photoredox C-H arylation of anthranils is reported. A variety of aryl diazonium tetrafluoroborates were used as aryl sources, providing the C3 cross-coupled products. The in situ generated reactive radicals were trapped by anthranils, providing an alternative method to transition-metal-catalyzed C-H arylations of anthranils. Gold-catalyzed downstream transformations demonstrate the synthetic potential of these valuable building blocks.