69751-74-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-3,5-dibromobenzophenone is used as a starting material for the synthesis of pharmaceuticals. Its unique structure allows for the development of new drugs and treatments, making it a valuable component in medicinal chemistry.
Used in Dye Industry:
In the dye industry, 2-amino-3,5-dibromobenzophenone serves as a starting material for the synthesis of various dyes. Its bromine-containing structure contributes to the color and stability of the resulting dyes, making it an important compound in this field.
Used in Plastics and Adhesives Production:
2-Amino-3,5-dibromobenzophenone is used as a photoinitiator in the production of plastics and adhesives. Its ability to initiate polymerization reactions upon exposure to light makes it a useful component in the manufacturing process of these materials.
Used in Research and Development:
Due to its potential biological activity, 2-amino-3,5-dibromobenzophenone is being studied for its role in the development of new drugs and treatments. Researchers are exploring its properties and interactions with biological systems to better understand its potential applications in medicine.
It is important to handle 2-amino-3,5-dibromobenzophenone with care, as it may have hazardous properties and should be used in a controlled laboratory setting to ensure safety.

InChI:InChI=1/C13H9Br2NO/c14-9-6-10(12(16)11(15)7-9)13(17)8-4-2-1-3-5-8/h1-7H,16H2

Upstream product

• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 5840-40-4 2-nitrodiphenylmethane 
• 7726-95-6 bromine 
• 79-34-5 1,1,2,2-tetrachloroethane 
• 88092-64-2 2-Acetylamino-3,5-dibromobenzophenone 
• 2243-79-0 2-nitrobenzophenone 
• 552-89-6 2-nitro-benzaldehyde 
• 5176-14-7 3-phenyl-2,1-benzoxazole 
• 39859-36-4 2-amino-5-bromobenzophenone 
• 885-34-7 5-Brom-3-phenyl-2,1-benzisoxazol 

Downstream Products

• 857550-45-9 1-(2-amino-3,5-dibromo-phenyl)-1-phenyl-propan-1-ol 
• 7141-05-1 (2-amino-5-bromophenyl)phenylmethanol 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 615-57-6 2,4-dibromo-aniline 
• 65-85-0 benzoic acid 
• 92646-08-7 1-(2-aminophenyl)-1-phenyl-1-propanol 
• 85-99-4 2-acetamidobenzophenone 
• 70593-68-9 2,2''-azo-di-benzophenone 
• 13209-38-6 (2-aminophenyl)(phenyl)methanol 

Relevant academic research and scientific papers

Structure-Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin

High-throughput screening has shown that Retro-1 inhibits ricin and Shiga toxins by diminishing their intracellular trafficking via the retrograde route, from early endosomes to the Golgi apparatus. To improve the activity of Retro-1, a structure-activity relationship (SAR) study was undertaken and yielded an analogue with a roughly 70-fold better half-maximal effective concentration (EC50) against Shiga toxin cytotoxicity measured in a cell protein synthesis assay.

Single-Step Synthesis of 3-Iodoquinolines from 2-Aminophenyl Ketones through a Regioselective (6-endo-dig) Electrophilic Cyclization

A highly facile single-step synthetic approach to 3-iodoquinolines has been developed for the first time from readily available 2-aminobenzophenones and terminal alkynes. The reaction involves the nucleophilic addition of terminal alkynes to 2-aminobenzophenones followed by a regioselective iodocyclization (6-endo-dig) to furnish 2,4-disubstituted 3-iodoquinolines in high yields. In general, 2,4-diaryl-substituted products were isolated without the need for column chromatography.