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51803-78-2

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Product FOB Price Min.Order Supply Ability Supplier
Nimesulide China Manufacturer
Cas No: 51803-78-2
USD $ 100.0-2000.0 / Gram 10 Gram 5000 Kilogram/Month SHANGHAI KAIWODUN BIOCHEMICAL CO.,LTD Contact Supplier
Nimesulide Manufacturer/High quality/Best price/In stock
Cas No: 51803-78-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Active Pharmaceutical Ingredient Nimesulide For Anti-inflammatory
Cas No: 51803-78-2
USD $ 0.9-1.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Hubei Yuancheng Saichuang Technology Co., Ltd Contact Supplier
Factory supply high quality Nimesulide Cas 51803-78-2 with reasonable price
Cas No: 51803-78-2
USD $ 42.0-45.0 / Kilogram 25 Kilogram 70 Metric Ton/Year Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
High quality Nimesulide supplier in China
Cas No: 51803-78-2
No Data No Data No Data Simagchem Corporation Contact Supplier
Chinese Nimesulide supplier/suppliers manufacturer factory
Cas No: 51803-78-2
No Data No Data 1000 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier
nimesulide/high quality/manufacturer/hot sale
Cas No: 51803-78-2
No Data 10 Gram 200 Kilogram/Month Hubei Jusheng Technology Co., Ltd., Contact Supplier
TIANFU-CHEM CAS:51803-78-2 Nimesulide
Cas No: 51803-78-2
No Data 1 Gram 1 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Nimesulide
Cas No: 51803-78-2
USD $ 1.0-1.5 / Gram 1 Gram 1-100 Metric Ton/Month Baowei Technology Qinhuangdao Co., Ltd Contact Supplier
Nimesulide CAS 51803-78-2
Cas No: 51803-78-2
USD $ 75.0-100.0 / Kilogram 1 Kilogram 15 Metric Ton/Month HUBEI AOKS TRADE CO.,LTD Contact Supplier

51803-78-2 Usage

References

https://en.wikipedia.org/wiki/Nimesulide
https://www.drugbank.ca/drugs/DB04743

Biological Activity

Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo . Reported to produce fewer gastrointestinal side effects than standard NSAIDs.牋.

Uses

Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 μM for human recombinant COX-1 and -2 (at 20 μM arachidonic acid), respectively, and 22 and 0.03 μM for ovine COX-1 and -2 (at 100 μM arachidonic acid), respectively.[Cayman Chemical]

Uses

Labelled Nimesulide . Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.;Labeled Nimesulide, intended for use as an internal standard for th

Uses

Antiinflammatory;'Cyclooxygenase 2 inhibitor

Description

Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. It is indicated for the treatment of acute pain, symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults. However, due to the risk of causing hepatotoxicity, it should not be taken long-term. It has also been withdrawn from the markets in many countries. It mechanism of action is through targeting on various key mediators in the inflammatory process such as COX-2 mediated prostaglandins, free radicals, proteolytic enzymes and histamine.

Chemical Properties

Yellow Needle-Like Crystals

Uses

Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production

Uses

Labelled Nimesulide (N477500). Antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-α production.

Uses

For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.

51803-78-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (N1016)  Nimesulide   51803-78-2 N1016-25G 3,498.30CNY Detail
Sigma (N1016)  Nimesulide   51803-78-2 N1016-5G 883.35CNY Detail
Sigma (N1016)  Nimesulide   51803-78-2 N1016-1G 253.89CNY Detail
Sigma-Aldrich (Y0001237)  Nimesulide for peak identification  European Pharmacopoeia (EP) Reference Standard 51803-78-2 Y0001237 1,880.19CNY Detail
Sigma-Aldrich (N0845000)  Nimesulide  European Pharmacopoeia (EP) Reference Standard 51803-78-2 N0845000 1,880.19CNY Detail
TCI America (N0984)  Nimesulide  >98.0%(HPLC)(T) 51803-78-2 5g 690.00CNY Detail
TCI America (N0984)  Nimesulide  >98.0%(HPLC)(T) 51803-78-2 1g 190.00CNY Detail

51803-78-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name nimesulide

1.2 Other means of identification

Product number -
Other names Mesulid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51803-78-2 SDS

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