5198-48-1

Basic information

• Product Name: 2-Oxazolidinone, 3-(4-methoxyphenyl)-
• CAS NO: 5198-48-1
• Molecular Formula: C10H11NO3
• Molecular Weight: 193.202
• Mol File: 5198-48-1.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-(4-methoxyphenyl)-(5198-48-1)
• EPA Substance Registry System: 2-Oxazolidinone, 3-(4-methoxyphenyl)-(5198-48-1)

Safety Data

• Hazardous Substances Data: 5198-48-1(Hazardous Substances Data)

Upstream product

• 497-25-6 dimethylenecyclourethane 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 18437-68-8 tert-butyl N-(4-methoxyphenyl)carbamate 
• 75-21-8 oxirane 
• 124-38-9 carbon dioxide 
• 104-94-9 4-methoxy-aniline 
• 107-06-2 1,2-dichloro-ethane 
• 106-93-4 ethylene dibromide 
• 627-11-2 2-Chloroethyl chloroformate 
• 5602-93-7 ethyl (2-hydroxyethyl)carbamate 
• 196804-36-1 (4-methoxy-phenyl)-carbamic acid-(2-chloro-ethyl ester) 
• 26690-80-2 2-(N-tert-butoxycarbonylamino)ethanol 
• 96-49-1 [1,3]-dioxolan-2-one 

Downstream Products

• 33141-33-2 3-(4-methoxyphenylamino)propanenitrile 
• 2933-77-9 N-(2-hydroxyethyl)-4-methoxyaniline 
• 28690-23-5 3-(4-methoxyphenyl)thiazolidin-2-one 
• 1313524-89-8 C₁₆H₁₃F₂NO₃ 

Relevant articles and documents

The Synthesis of 3-Aryl-2-oxazolidinones from CO2, Ethylene Oxide, and Anilines Under Mild Conditions Using PVA-DFNT/Ni

Abstract: A novel nanocatalyst design using nanomaterials through active-zone crystallisation was proposed. The hydrothermal crystallisation of amorphous dendritic fibrous nano-titanium dioxide with Ni (DFNT/Ni) sites was determined to be the main step in producing extremely active dendritic DFNT/Ni zones, which in turn dramatically enhanced their catalytic activities. DFNT/Ni was then combined with polyvinyl alcohol (PVA) by using a traditional individual-nozzle electrospinning method, and the resulting material was named PVA-DFNT/Ni. This method was utilised to produce 3-aryl-2-oxazolidinones from ethylene oxide, CO2, and anilines. The prepared catalytic apparatus was eco-friendly and had the advantages of high catalytic activity, ability to improve the reaction mixture, and reusability without a considerable decrease in efficiency. It is extracted in the straight and adoptive chemical fixation of flue-gas CO2 obtained from industrial emissions, thereby achieving high degrees of CO2 absorption and conversion. Graphic Abstract: [Figure not available: see fulltext.].

Method for synthesizing cyclic amide from carbon dioxide

The invention discloses a method for synthesizing cyclic amide from carbon dioxide. An aromatic amino compound, 1 atm carbon dioxide and a halogenated compound undergo a one-step reaction under the synergistic action of N-doped TiO2 and an inorganic salt catalyst to generate the cyclic amide. Studies find that visible light has an obvious promoting effect on the conversion process. The chemical selectivity of the cyclic amide compound can be regulated by regulating conditions such as reaction temperature, time and illumination. The catalyst can be recycled for five times after being separatedand dried, and the activity and the chemical selectivity can be well maintained. The synthesis method has the advantages of simple synthetic route, novelty, simple process, high yield and high purityof the product, cheap and easily available catalyst, no influences on the environment, and suitableness for industrial production.

Synthesis of N-aryl-2-oxazolidinones from cyclic carbonates and aromatic amines catalyzed by bio-catalyst

A convenient and effective method of synthesizing 3-aryl-2-oxazolidinones from cyclic carbonates and aryl amines catalyzed by bio-catalyst adenine in the presence of Et3N under solvent-free conditions is described. The protocol is suitable for the wide scope of substrates, e.g. cyclic carbonates with or without substitutes, and aryl amines with either electron-withdrawing or electron-donating group. The products were obtained in good to excellent yields under the optimal conditions, even in steric hindered cases. The effect of reaction time, temperature, loading of catalyst, and amount of starting materials in the reaction were investigated, and the reaction mechanism is discussed.