52334-90-4

Basic information

• Product Name: 4-Amino-3-methoxypyridine
• Synonyms: 4-Amino-3-methoxypyridine;3-methoxy-4-aminopyridine;3-Methoxypyridin-4-amine;3-Methoxy-4-PyridinaMine;3-Methoxy-pyridin-4-ylamine
• CAS NO: 52334-90-4
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14052
• EINECS: 214-589-6
• Product Categories: Pyridine series;API intermediates;Building Blocks;Pyridine
• Mol File: 52334-90-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 94.5-95.5 °C
• Boiling Point: 277.8 °C at 760 mmHg
• Flash Point: 121.8 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 0.00442mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.11±0.10(Predicted)
• CAS DataBase Reference: 4-Amino-3-methoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3-methoxypyridine(52334-90-4)
• EPA Substance Registry System: 4-Amino-3-methoxypyridine(52334-90-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 52334-90-4(Hazardous Substances Data)

Usage

Uses

3-Methoxy-4-pyridinamine, is a building block used in various chemical synthesis.

InChI:InChI=1/C6H8N2O/c1-9-6-4-8-3-2-5(6)7/h2-4H,1H3,(H2,7,8)

Upstream product

• 1336-21-6 ammonium hydroxide 
• 19355-04-5 3-methoxy-4-nitropyridine 1-oxide 
• 75-09-2 dichloromethane 
• 7295-76-3 3-methoxypyridine 
• 14906-61-7 3-methoxypyridine N-oxide 

Downstream Products

• 127356-39-2 4-amino-3-methoxy-5-nitropyridine 
• 1620292-59-2 phenyl (3-methoxypyridin-4-yl)carbamate 
• 1303557-53-0 [2-(5-chloro-2-fluoro-phenyl)-quinolin-4-yl]-(3-methoxy-pyridin-4-yl)-amine 
• 52334-53-9 4-amino-3-hydroxy pyridine 
• 127356-09-6 2-(4-Methanesulfinyl-2-methoxy-phenyl)-7-methoxy-1H-imidazo[4,5-c]pyridine 
• 127356-31-4 7-Methoxy-2-(2-methoxy-4-methylsulfanyl-phenyl)-1H-imidazo[4,5-c]pyridine 
• 127356-27-8 3,4-diamino-5-methoxypyridine 

Relevant articles and documents

Heterocyclic compound used as MNK inhibitor

The invention relates to a heterocyclic compound, a pharmaceutical composition containing the heterocyclic compound, a preparation method thereof, and application thereof used as a mitogen activated protein kinase interacting kinase 1 and 2-MNK1/MNK2 inhibitor. The inhibitor is the heterocyclic compound as shown in the formula (I), or its pharmaceutically acceptable salt, prodrug, solvent compound, polycrystal, isomer, stable isotope derivative or a pharmaceutical composition containing the heterocyclic compound. The compound of the invention can be used for treating or preventing MNK-mediatedrelated diseases, such as cancers.

Preparation of pyrido-1,4-oxazinylalkyl-benzamides for treating diseases mediated by platelet activating factor.

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