52399-93-6

Usage

Uses

Used in Chemical Industry:
1,2-Dichlor-aethan is used as a solvent for the production of cellulose esters, such as cellulose acetate and cellulose acetate butyrate, which are important materials in the manufacturing of films, fibers, and plastics.
Used in Dye Industry:
1,2-Dichlor-aethan is used as a solvent in the manufacturing of dyes, facilitating the process of dye synthesis and application.
Used in Pharmaceutical Industry:
1,2-Dichlor-aethan is used as a solvent in the production of various pharmaceuticals, aiding in the synthesis and formulation of drugs.
Used in Organic Chemical Production:
1,2-Dichlor-aethan serves as an intermediate in the production of a range of organic chemicals, contributing to the synthesis of various compounds used in different industries.
However, it is crucial to note that 1,2-Dichlor-aethan is known to be toxic and a potential carcinogen. Exposure to high levels of 1,2-Dichlor-aethan [German] can lead to respiratory and central nervous system depression, as well as liver and kidney damage. Therefore, it is essential to handle and use 1,2-Dichlor-aethan with caution, adhering to safety guidelines and regulations to minimize health risks and environmental impact.

InChI:InChI=1/C2H4Cl2/c3-1-2-4/h1-2H2

Upstream product

• 75-21-8 oxirane 
• 5813-48-9 Methanesulfenyl chloride 
• 74-87-3 methylene chloride 
• 13891-58-2 chloroethyl chlorosulfate 
• 62516-55-6 sulfurous acid bis-(2-chloro-ethyl ester) 
• 5411-48-3 sulfuric acid bis-(2-chloroethyl) ester 
• 115-96-8 Tris(2-chloroethyl) phosphate 
• 64-17-5 ethanol 
• 98020-30-5 dichloro-(2-chloro-ethoxy)-acetyl chloride 
• 74-85-1 ethene 
• 75-00-3 chloroethane 
• 505-60-2 bis (2-chloroethyl) sulphide 
• 6719-83-1 chlorophosphoric acid-(2-chloro-ethyl ester)-phenyl ester 
• 16670-48-7 2-chloroethyl benzenesulfonate 

Downstream Products

• 7473-43-0 tetra-O-benzoyl-β-D-ribopyranose 
• 4593-20-8 1-chloroacetyl-4-methyl-piperidine 
• 64236-22-2 10-methyl-N-phenylacridine-9(10H)-imine 
• 94823-13-9 dichloro-acetic acid-[(2,4-dichloro-benzyl)-(3-piperidino-propyl)-amide] 
• 98334-15-7 (+/-)-trichloromethanesulfenic acid-(trans-2-chloro-cyclohexyl ester) 
• 69614-95-5 1-(4-(2-chloroethyl)phenyl)ethan-1-one 
• 101278-82-4 azulen-1-yl-(2,4-dinitro-phenyl)-sulfide 
• 4013-98-3 N,N'-dicyclohexylethylenediamine 
• 7244-02-2 (ethylenedithio)diacetic acid 
• 37102-72-0 1,2-bis-bromoacetoxy-propane 
• 29517-80-4 (2-chloro-ethyl)-m-tolyl ether 
• 21120-79-6 1-(2-chloroethoxy)-2-methylbenzene 
• 7784-99-8 1-methoxy-2-vinyloxybenzene 
• 31512-74-0 N,N'-bis-(2-acetoxy-ethyl)-N,N,N',N'-tetramethyl-N,N'-ethanediyl-di-ammonium; dichloride 

Relevant academic research and scientific papers

Method for producing chloroethanol and dichloroethane through ethylene glycol chlorination

The invention relates to a method for producing chloroethanol and dichloroethane through ethylene glycol chlorination. According to the method, ethylene glycol is taken as a raw material, a cobalt compound, a manganese compound and an iron compound are taken as active components, and a zinc compound is taken as an active catalyst of an active auxiliary agent, so that the reaction of chloroethanol and dichloroethane can be effectively catalyzed, and high chloroethanol yield is obtained. The method solves the problems of poor selectivity and difficulty in organic acid catalyst recovery in the chloroethanol and dichloroethane preparation reaction in the prior art, and also avoids the problems of high ethylene oxide production cost, difficulty in storage and transportation and the like in the chloroethanol process taking ethylene oxide as a raw material.

Method of Converting a Brominated Hydrocarbon to a Chlorinated Hydrocarbon

The present invention provides a method of converting a brominated hydrocarbon to a chlorinated hydrocarbon that involves contacting together the brominated hydrocarbon and a chlorinated ion exchange resin that has a water content of less than or equal to 30 percent by weight, based on the total weight of the chlorinated ion exchange resin and the water. The brominated hydrocarbon includes at least one replaceable bromo group, where each replaceable bromo group is independently covalently bonded to an sp3 hybridized carbon. Contact between the brominated hydrocarbon and the chlorinated ion exchange resin results in replacement of at least one replaceable bromo group of the brominated hydrocarbon with a chloro group, and correspondingly conversion of at least a portion of the brominated hydrocarbon to the chlorinated hydrocarbon.

Nitrogen-Doped Carbon-Assisted One-pot Tandem Reaction for Vinyl Chloride Production via Ethylene Oxychlorination

A bifunctional catalyst comprising CuCl2/Al2O3 and nitrogen-doped carbon was developed for an efficient one-pot ethylene oxychlorination process to produce vinyl chloride monomer (VCM) up to 76 % yield at 250 °C and under ambient pressure, which is higher than the conventional industrial two-step process (≈50 %) in a single pass. In the second bed, active sites containing N-functional groups on the metal-free N-doped carbon catalyzed both ethylene oxychlorination and ethylene dichloride (EDC) dehydrochlorination under the mild conditions. Benefitting from the bifunctionality of the N-doped carbon, VCM formation was intensified by the surface Cl*-looping of EDC dehydrochlorination and ethylene oxychlorination. Both reactions were enhanced by in situ consumption of surface Cl* by oxychlorination, in which Cl* was generated by EDC dehydrochlorination. This work offers a promising alternative pathway to VCM production via ethylene oxychlorination at mild conditions through a single pass reactor.

Continuous method for preparation of dihalogenated alkane from diol compound

The invention discloses a continuous method for preparation of dihalogenated alkane from a diol compound. A diol compound and haloid acid are used as the substrate, a microchannel reactor is utilizedto synthesize dihalogenated alkane continuously. Synthesis of the dihalogenated alkane includes the steps of: inputting the diol compound and haloid acid into a mixer respectively by a metering pump at room temperature, conducting premixing, then sending the mixture into a high-temperature section of the microchannel reactor at for reaction, and controlling the reaction temperature by an externalcirculating heat exchange system; at the end of the reaction, letting the product flow out from an outlet of the microchannel reactor and enter a cooling section, letting the cooled material enter a liquid separation kettle for standing and liquid separation, and collecting an organic layer; and preheating the organic layer, then feeding the preheated organic layer into a rectifying tower by a metering pump, controlling the temperature and reflux ratio of a reboiler, and collecting fractions at a specific temperature, thus obtaining the target product in a product collecting tank. The method provided by the invention has the characteristics of high reaction efficiency, safety, environmental protection, convenience and rapidity.

Deactivation factor of CuCl2-KCl/Al2O3 catalyst for ethylene oxychlorination in a commercial-scale plant

Ethylene oxychlorination over a CuCl2-KCl/Al2O3 catalyst was examined for 2 consecutive years in a commercial-scale plant. The oxychlorination performance of the CuCl2-KCl/Al2O3 catalyst deteriorated gradually, which could seriously affect stable operation. To clarify such deactivation factors, the relationship between catalyst performance and physicochemical property change was investigated using X-ray fluorescence, electron probe microanalysis, and Brunauer–Emmett–Teller measurements. Sublimation of the CuCl component and subsequent increment of the ratio of K to Cu components were observed at the inlet of the catalyst bed, and were determined to be contributing factors in the deactivation of the CuCl2-KCl/Al2O3 catalyst.

Method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane

The invention relates to a method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane, belonging to the field of organic chemical synthesis. The method for synthesizing 1,2-difluoroethane and 1,1,2-trifluoroethane is characterized in that ethylene (with a molecular formula of CH2=CH2) and chlorine (with a molecular formula of Cl2) are heated under the action of a catalyst to generate a mixture of 1,2-dichloroethane and 1,1,2-trichloroethane, and the mixture and hydrogen fluoride (with a molecular formula HF) are heated under the action of a fluorination catalyst to generate 1,2-difluoroethane and 1,1,2-trifluoroethane. According to the method, raw materials are low in process and convenient to obtain; product separation and purification are simple; industrial production is easy;and industrial three-waste generation amount is low.

SYSTEMS AND METHODS USING LANTHANIDE HALIDE

There are provided methods and systems related to use of one or more lanthanide halides in an electrochemical oxidation of metal halide in anolyte where the metal ion is oxidized from lower oxidation state to higher oxidation state at an anode; and then further use of the one or more lanthanide halides and the metal halide with the metal ion in the higher oxidation state in a halogenation reaction of an unsaturated hydrocarbon or a saturated hydrocarbon to form one or more products comprising halohydrocarbon.

Preserved in a Shell: High-Performance Graphene-Confined Ruthenium Nanoparticles in Acetylene Hydrochlorination

The potential implementation of ruthenium-based catalysts in polyvinyl chloride production via acetylene hydrochlorination is hindered by their inferior activity and stability compared to gold-based systems, despite their 4-fold lower price. Combining in-depth characterization and kinetic analysis we reveal the superior activity of ruthenium nanoparticles with an optimal size of 1.5 nm hosted on nitrogen-doped carbon (NC) and identify their deactivation modes: 1) nanoparticle redispersion into inactive single atoms and 2) coke formation at the metal sites. Tuning the density of the NC carrier enables a catalytic encapsulation of the ruthenium nanoparticles into single layer graphene shells at 1073 K that prevent the undesired metal redispersion. Finally, we show that feeding O2 during acetylene hydrochlorination limits coke formation over the nanodesigned ruthenium catalyst, while the graphene layer is preserved, resulting in a stability increase of 20 times, thus rivalling the performance of gold-based systems.

Facile continuous process for gas phase halogen exchange over supported alkyl phosphonium salts

Chloride-bromide halogen exchange was realized when a mixture of an alkyl chloride and an alkyl bromide were reacted over a supported molten alkyl phosphonium catalyst. Conversion was found to be near equilibrium in a tubular flow reactor at 150 °C and 1500 GHSV. The catalyst was prepared by impregnation of alumina or silica support and found to be highly stable for relatively long periods of time. A pathway for the catalytic cycle is proposed.

1, 2 - dichloroethane production

PROBLEM TO BE SOLVED: To provide a novel method for manufacturing 1,2-dichloroethane capable of manufacturing, from ethylene in a high yield, 1,2-dichloroethane useful as a raw ingredient of a vinyl chloride monomer.SOLUTION: The provided method for manufacturing 1,2-dichloroethane uses, on an occasion for manufacturing 1,2-dichloroethane by inducing, in the presence of an oxychlorination catalyst, an oxychlorinating reaction of ethylene, hydrogen chloride, and air, a serial oxychlorination reaction process equipped with at least two fixed bed circulation-type catalytic reaction columns and executes an oxychlorinating reaction by filling, into the rearmost downstream-side fixed bed circulation-type catalytic reaction column of the serial oxychlorination catalytic reaction process, a hollow cylindrical oxychlorination catalyst (1) including, within a carrier, at least copper chloride and one or more types of metal cation halides having coordinated water exchanging reaction velocities of below 1×10sat 298K.