5267-47-0Relevant academic research and scientific papers
Air-stable Bis(pentamethylcyclopentadienyl) Zirconium Perfluorooctanesulfonate as an Efficient and Recyclable Catalyst for the Synthesis of N-substituted Amides
Li, Ningbo,Wang, Lingxiao,Zhang, Liting,Zhao, Wenjie,Qiao, Jie,Xu, Xinhua,Liang, Zhiwu
, p. 3532 - 3538 (2018/08/01)
Bis(pentamethylcyclopentadienyl) zirconium perfluorooctanesulfonate is an air-stable and water-tolerant Lewis acid. This complex exhibited good thermal stability and high solubility in polar organic solvents. The compound showed relatively strong acidity, with an acid strength of 0.8Ho≤3.3, and high catalytic efficiency for the synthesis of N-substituted amides via the reaction of carboxylic acids with amines, the Ritter reaction of nitriles with alcohols, and the amination of alcohols with amides. Moreover, the complex had good reusability. This catalytic system affords a simple and efficient way to synthesize N-substituted amides.
Microwave assisted, Ca(II)-catalyzed Ritter reaction for the green synthesis of amides
Yaragorla, Srinivasarao,Singh, Garima,Lal Saini, Pyare,Reddy, M. Kesava
, p. 4657 - 4660 (2014/12/10)
An efficient solvent-free synthesis of amides by Ca(II) catalyzed Ritter reaction has been reported under microwave irradiation. This green protocol tolerates the substrate diversity and delivers the high yielding amides with minimal loading of inexpensive and more abundant Ca(II) catalyst.
Bis-sulfamyl imines: Potent substrates for asymmetric additions of arylboroxines under rhodium catalysis
Crampton, Rosemary,Woodward, Simon,Fox, Martin
supporting information; experimental part, p. 903 - 906 (2011/06/19)
Bis-sulfamyl imines are shown to be potentially ideal substrates for rhodium-catalysed asymmetric additions of arylboron nucleophiles as they show: (i) near perfect enantioselectivities (11 examples, 98-99+% ee), (ii) good to excellent diastereoselectivities (10-32:1 rac:meso), and (iii) high functional group tolerance in removal of the low molecular weight protecting group via mild heating in aqueous pyridine.
o-Benzenedisulfonimide as a reusable Bronsted acid catalyst for Ritter-type reactions
Barbero, Margherita,Bazzi, Stefano,Cadamuro, Silvano,Dughera, Stefano
experimental part, p. 430 - 436 (2009/07/19)
Reactions between various benzyl alcohols or tert-butyl alcohol and nitriles were carried out in the presence of catalytic amounts (usually 10-20 mol-%) of o-benzenedisulfonimide as a Bronsted acid catalyst; the reaction conditions were mild and the yields of amides were good. The catalyst was easily recovered and purified, ready to be used in further reactions, with economic and ecological advantages. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.
α-Amidobenzylation of aryl and alkenyl halides via palladium-catalyzed Suzuki-Miyaura coupling with α-(acylamino) benzylboronic esters
Ohmura, Toshimichi,Awano, Tomotsugu,Suginome, Michinori
, p. 664 - 665 (2011/04/22)
The Suzuki-Miyaura coupling of α-(acetylamino)benzylboronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)3 catalyst with KF and H2O in 1,4-dioxane, giving α-substituted benzylamines in high yields. Copyright
Molecular iodine-catalysed amidation reaction of secondary benzylic and allylic alcohols with carboxamides or sulfonamides
Lin, Xufeng,Wang, Jun,Xu, Fangxi,Wang, Yanguang
experimental part, p. 638 - 641 (2011/03/18)
A highly efficient method for the C-N bond formation via 2 mol% of molecular iodine-catalysed amidation reaction of benzylic and allylic alcohols with carboxamides or sulfonamides in MeCN is described, giving the corresponding substituted amides and allyl
Three-component synthesis of amine derivatives using benzylic and allylic alcohols as N-alkylating agents in the absence of external catalysts and additives
Li, Hai-Hua,Dong, De-Jun,Tian, Shi-Kai
experimental part, p. 3623 - 3626 (2009/05/07)
The direct employment of benzylic and allylic alcohols as N-alkylating agents provides a useful synthetic route for amine derivatives by avoiding the preactivation of the hydroxy groups of alcohols. Herein we report a novel by-product-catalyzed three-comp
A convenient protocol for C-H oxidation mediated by an azido radical culminating in Ritter-type amidation
Nair, Vijay,Suja,Mohanan, Kishor
, p. 3217 - 3219 (2007/10/03)
Cerium(IV) ammonium nitrate in combination with sodium azide reacts with unactivated hydrocarbons in acetonitrile to furnish acetamides in one pot. The strategy can be used to introduce nitrogen functionality into a variety of compounds; a carboxylic ester directly afforded the corresponding α-amino acid.
