52864-94-5

Upstream product

• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 
• 108-98-5 thiophenol 
• 130-15-4 [1,4]naphthoquinone 
• 57341-12-5 2-phenylsulfanyl-[1,4]naphthoquinone 
• 31519-22-9 1,4-dihydroxy-2-naphthoic acid 
• 571-60-8 1,4-Dihydroxynaphthalene 
• 882-33-7 diphenyldisulfane 
• 2065-37-4 2-bromo-1,4-naphthoquinone 
• 38957-35-6 2,3-bis(benzotriazol-1-yl)-1,4-naphthoquinone 
• 75-64-9 tert-butylamine 
• 3114-98-5 2-bromo-3-thiophenyl-1,4-naphthoquinone 
• 3111-52-2 potassium thiophenolate 

Relevant academic research and scientific papers

Synthesis and?evaluation of?antifungal activity of?naphthoquinone derivatives

3-Arylamino-2-phenylsulfinylnaphthoquinones, 2,3-diarylthio-naphthoquinones and 2-phenylsulfinyl-3-arylthio-1,4-dihydronaphtalenes are synthesized and tested against five fungi. The activities of these products were better than amphotericine B against all

Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents

A series of 1,4-naphthoquinone derivatives were synthesized and tested for antifungal and antitumor activity against a number of fungal disease causative species and Walker 256 carcinoma cell lines. The results show that the compounds 8a,e and 11b possess

Quinone-based fluorophore: A promising luminescent functional material for effective sensing of serine

In the recent decade, the redox-active quinone entity has been exhaustively evaluated as a potential drug-like molecule. However, there are only few reports that have demonstrated its applicability as a sensor-like motif against biological analytes. In pu

NAPHTHAQUINONE METHYLTRANSFERASE INHIBITORS AND USES THEREOF

Provided herein are compounds of (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions and methods involving the inventive compounds for the treatment of proliferative diseases (e.g., cancer (e.g., leukemia, breast cancer, melanoma, metastatic cancer) and diseases associated with inappropriate SET8 activity. Also provided are methods for inhibiting SET8 and methods for labelling SET8.

A one-pot synthesis of 1,4-naphthoquinone-2,3-bis-sulfides catalysed by a commercial laccase

Oxidative C-S bond formation with aryl and alkyl thiols was catalysed under mild conditions in a reaction vessel open to air at pH 4.5 and 7.15 in the presence of a commercial laccase (Novozym 51003) and a co-solvent (DMF) to afford 1,4-naphthoquinone-2,3

Synthesis and selective anticancer activity of organochalcogen based redox catalysts

Many tumor cells exhibit a disturbed intracellular redox state resulting in higher levels of reactive oxygen species (ROS). As these contribute to tumor initiation and sustenance, catalytic redox agents combining significant activity with substrate specif

2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: Synthesis and Biological evaluation as potential antiproliferative and antifungal agents

A series of 2-chloro-3-arylsulfanyl-[1,4]naphthoquinones (2), 2,3-bis-arylsulfanyl-[1,4]naphthoquinones (3) and 12H-benzo[b]phenothiazine-6,11-diones and their analogs 6-8 were synthesized and evaluated for their antiproliferative activity against human c

Synthesis of mixed aryl 2,3-diarylsulphanyl-1,4-naphthoquinones

The reaction of 2-arylsulphanyl-1,4-napththoquinone with aromatic thiols and sodium dithionate leads to bis-2,3-(arylsulphanyl)naphthalene-1,4-diols in high yield. Corresponding oxidized products, namely 2,3-diarylsulphanyl-1,4- naphthoquinones, are prepa