Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents

Article abstract of DOI:10.1016/j.bmcl.2004.01.002

A series of 1,4-naphthoquinone derivatives were synthesized and tested for antifungal and antitumor activity against a number of fungal disease causative species and Walker 256 carcinoma cell lines. The results show that the compounds 8a,e and 11b possess