5347-18-2

Upstream product

• 75-15-0 carbon disulfide 
• 109-89-7 diethylamine 
• 148-18-5 sodium N,N-diethyldithiocarbamate 
• 540-51-2 2-bromoethanol 
• 147-84-2 Diethyldithiocarbamic acid 
• 107-07-3 2-chloro-ethanol 
• 96-49-1 [1,3]-dioxolan-2-one 

Downstream Products

• 29000-97-3 [2-(2,4-Dichloro-phenoxy)-acetyl]-carbamic acid 2-diethylthiocarbamoylsulfanyl-ethyl ester 
• 29000-96-2 (2-o-Tolyloxy-acetyl)-carbamic acid 2-diethylthiocarbamoylsulfanyl-ethyl ester 
• 29000-94-0 Benzoyl-carbamic acid 2-diethylthiocarbamoylsulfanyl-ethyl ester 
• 29000-95-1 (4-Nitro-benzoyl)-carbamic acid 2-diethylthiocarbamoylsulfanyl-ethyl ester 
• 29082-30-2 (4-Chloro-benzoyl)-carbamic acid 2-diethylthiocarbamoylsulfanyl-ethyl ester 
• 121527-57-9 diethyl-[1,3]dithiolan-2-yliden-ammonium; tetraphenyl borate 

Relevant academic research and scientific papers

METHOD FOR PREPARING DITHIOCARBAMATES IN PARTICULAR FROM POLYOLS OF THE GLYCEROL TYPE

The present invention concerns a method for the synthesis of glycerol dithiocarbamates or bis-dithiocarbamates (GDTCs) in which a reaction medium comprising (1) a carbonate selected from diethyl carbonate, dimethyl carbonate and ethylene or propylene carbonate associated with a glycerol type polyol in the presence of a basic catalyst or (2) a cyclic carbonate comprising five ring members, in a solvent medium, is supplemented with a primary or secondary amine in the presence of carbon disulphide, and the GDTC formed is recovered. In particular, a glycerol type polyol is brought into the presence of diethyl carbonate in the presence of a catalyst, then a primary or secondary amine is added to the reaction medium in the presence of carbon disulphide, and the GDTC formed is recovered. The invention can be used for one-step synthesis of glycerol dithiocarbamates directly from glycerol as the starting material and solvent. This method involves glycerol, diethyl carbonate, carbon disulphide (CS2) and a primary or secondary amine to produce glycerol dithiocarbamates; the glycerol/NaOH phase can be recycled 6 times without a noticeable drop in yield; the ethyl acetate is also recycled after each extraction.

Regioselective functionalization of glycerol with a dithiocarbamate moiety: An environmentally friendly route to safer fungicides

We report here a convenient pathway for the direct functionalization of glycerol with a dithiocarbamate moiety. This work opens up a cost-efficient and environmentally friendly route to safer fungicides. It should be noted that whereas functionalization of glycerol usually suffers from a lack of selectivity, we show here that our process is fully regioselective.