5351-01-9Relevant articles and documents
The Heck reaction in the presence of molecular oxygen
Hosokawa, Takahiro,Kamiike, Taisuke,Murahashi, Shun-Ichi,Shimada, Mamoru,Sugafuji, Toshihiro
, p. 9323 - 9325 (2007/10/03)
Palladium-catalyzed reaction of CH2=C(R)COOMe (R=H or CH2OH) with PhI in the presence of NEt3 under O2 induces the oxidative dealkylation of NEt3, affording either methyl 3-diethylaminopropionate (3) or methyl (Z)-2-benzyl-3-(N,N′-diethylamino)propenate (6), in case of R=H or R=CH2OH, respectively.
REACTION OF VINYL ESTERS OF α,β-UNSATURATED CARBOXYLIC ACIDS WITH SECONDARY AMINES
Komarova, L. I.,Lomanovskaya, T. D.,Komarov, N. V.
, p. 1624 - 1627 (2007/10/02)
It was established that the double bond of the acrylic system is more reactive in the reactions of vinyl acrylate and allyl acrylate with secondary amines and that the reaction of secondary amines with vinyl trans-crotonate and cinnamate takes place regioselectively at the double bond of the vinyloxy group.Methods were found for the production of vinyl and allyl β-substituted aminopropionates and 2-alkylaminoethyl trans-crotonate and trans-cinnamate.