53566-73-7Relevant academic research and scientific papers
Ascorbic Acid Promoted Metal-Free Synthesis of Aryl Sulfides with Anilines Nitrosated in Situ by tert -Butyl Nitrite
Bu, Mei-Jie,Lu, Guo-Ping,Cai, Chun
, p. 1841 - 1846 (2015)
A mild, metal-free synthesis of aryl sulfides has been disclosed. Aryl diazonium ion was generated by the in situ nitrosation of aniline, and it was reduced by ascorbic acid (vitamin C) to form aryl radical, which underwent a thiolation with disulfide to yield aryl sulfide. The reaction proceeded smoothly without heating or irradiation. This strategy was also expanded to the synthesis of aryl selenides.
Transition-Metal-Free and Oxidant-Free Cross-Coupling of Arylhydrazines with Disulfides: Base-Promoted Synthesis of Unsymmetrical Aryl Sulfides
Taniguchi, Toshihide,Naka, Takuya,Imoto, Mitsutaka,Takeda, Motonori,Nakai, Takeo,Mihara, Masatoshi,Mizuno, Takumi,Nomoto, Akihiro,Ogawa, Akiya
, p. 6647 - 6655 (2017/07/15)
A novel synthesis of unsymmetrical aryl sulfides, which requires no transition metal catalyst and no oxidant, was developed. This base-promoted cross-coupling reaction proceeded using arylhydrazines and 1 equiv amount of disulfides under inert gas conditions to afford the unsymmetrical aryl sulfides in good yields.
