53663-24-4 Usage
Uses
Used in Pharmaceutical Industry:
2,3,3-Triphenylpropanoic acid is utilized as a building block for the synthesis of various pharmaceuticals. Its role in drug development is pivotal, as it contributes to the creation of new medicinal compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,3-triphenylpropanoic acid serves as a fundamental component in the synthesis of different agrochemicals. This application underscores its importance in developing compounds that can enhance agricultural productivity and protect crops from pests and diseases.
Used in Organic Chemistry Research:
2,3,3-Triphenylpropanoic acid is employed as a chiral auxiliary in asymmetric synthesis. Its utility in this context is significant, as it aids in the production of enantiomerically pure compounds, which are essential in many chemical and pharmaceutical processes.
Used in Material Science:
2,3,3-Triphenylpropanoic acid has potential applications in the development of novel materials. Its unique properties make it a promising candidate for use in creating advanced materials with specific characteristics for various industries.
Used in Chemical Research:
As a reagent, 2,3,3-triphenylpropanoic acid is involved in various organic reactions, contributing to the advancement of chemical research. Its versatility in these reactions highlights its importance in the discovery and synthesis of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 53663-24-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,6 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 53663-24:
(7*5)+(6*3)+(5*6)+(4*6)+(3*3)+(2*2)+(1*4)=124
124 % 10 = 4
So 53663-24-4 is a valid CAS Registry Number.
53663-24-4Relevant academic research and scientific papers
Harnessing Applied Potential: Selective β-Hydrocarboxylation of Substituted Olefins
Alkayal, Anas,Buckley, Benjamin R.,Malkov, Andrei V.,Montanaro, Stephanie,Tabas, Volodymyr,Wright, Iain A.
supporting information, (2020/02/13)
The construction of carboxylic acid compounds in a selective fashion from low value materials such as alkenes remains a long-standing challenge to synthetic chemists. In particular, β-addition to styrenes is underdeveloped. Herein we report a new electrosynthetic approach to the selective hydrocarboxylation of alkenes that overcomes the limitations of current transition metal and photochemical approaches. The reported method allows unprecedented direct access to carboxylic acids derived from β,β-trisubstituted alkenes, in a highly regioselective manner.
Lewis acid-mediated β-selective hydrocarboxylation of α,α-diaryl- and α-arylalkenes with R3SiH and CO2
Tanaka, Shinya,Tanaka, Yuuki,Chiba, Masafumi,Hattori, Tetsutaro
, p. 3830 - 3834 (2015/06/08)
α,α-Diarylalkenes are successfully hydrocarboxylated with Et3SiH and CO2 with the aid of Et3SiB(C6F5)4 or EtAlCl2/Ph3SiCl to give carboxylic acids with a carboxy group at the β-position to the aryl groups. The EtAlCl2/Ph3SiCl-mediated reaction is also applicable to various α-arylalkenes. 1H NMR analysis of a mixture of EtAlCl2, Ph3SiCl, and Et3SiH strongly suggests the formation of a μ-H complex, [Ph3Si-H-SiEt3]+ AlEtCl3-, which is an equivalent of R3Si+ ions, while Et3SiB(C6F5)4 is an ion pair with a Et3Si+ ion. Therefore, in these reaction systems, a siloxycarbonylium, R3SiOCO+, is considered to be a common electrophile, the addition of which to the substrate, followed by trapping of the resulting cationic species with Et3SiH seems to afford the desired acid after aqueous workup.
