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5381-92-0

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5381-92-0 Usage

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 27, p. 2405, 1979 DOI: 10.1248/cpb.27.2405

Check Digit Verification of cas no

The CAS Registry Mumber 5381-92-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,8 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5381-92:
(6*5)+(5*3)+(4*8)+(3*1)+(2*9)+(1*2)=100
100 % 10 = 0
So 5381-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C15H16O/c16-15(11-13-7-3-1-4-8-13)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12H2

5381-92-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-diphenylpropan-2-ol

1.2 Other means of identification

Product number -
Other names 1,3-diphenyl-propan-2-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5381-92-0 SDS

5381-92-0Relevant academic research and scientific papers

Deprotonation des allylbenzenes chrometricarbonyle en milieu basique. Etude RMN 1H et 13C et reactivite des anions allyliques: influence electronique et sterique du groupement chrometricarbonyle

Senechal-Tocquer, M.C.,Senechal, D.,Bihan, J.Y. Le,Gentric, D.,Caro, B.,et al.

, p. 105 - 118 (1993)

1H and 13C NMR study of allylic anions obtained in basic media from allylbenzene Cr(CO)3 and propenylbenzene Cr(CO)3 or 2 is reported.A comparison with uncomplexed anions literature results allows to specify the structure of the anion and the ele

Direct and Unified Access to Carbon Radicals from Aliphatic Alcohols by Cost-Efficient Titanium-Mediated Homolytic C?OH Bond Cleavage

Suga, Takuya,Takahashi, Yuuki,Miki, Chinatsu,Ukaji, Yutaka

supporting information, (2022/01/31)

Low-valent Ti-mediated homolytic C?O bond cleavage offers unified access to carbon radicals from ubiquitous non-activated tertiary, secondary, and even primary alcohols. In contrast to the representative Ti reagents, which were ineffective for this purpos

Sulfonium ion-promoted traceless Schmidt reaction of alkyl azides

Ardiansah, Bayu,Kakiuchi, Kiyomi,Morimoto, Tsumoru,Tanimoto, Hiroki,Tomohiro, Takenori

supporting information, p. 8738 - 8741 (2021/09/08)

Schmidt reaction by sulfonium ions is described. General primary, secondary, and tertiary alkyl azides were converted to the corresponding carbonyl or imine compounds without any trace of the activators. This bond scission reaction through 1,2-migration of C-H and C-C bonds was accessible to the one-pot substitution reaction.

Homoleptic cobalt(II) phenoxyimine complexes for hydrosilylation of aldehydes and ketones without base activation of cobalt(II)

Hori, Momoko,Ishikawa, Ryuta,Koga, Yuji,Matsubara, Kouki,Mitsuyama, Tomoaki,Shin, Sayaka

, p. 1379 - 1387 (2021/05/29)

Air-stable, easy to prepare, homoleptic cobalt(II) complexes bearing pendant-modified phenoxyimine ligands were synthesized and determined. The complexes exhibited high catalytic performance for reducing aldehydes and ketones via catalytic hydrosilylation, where a hydrosilane and a catalytic amount of the cobalt(II) complex were added under base-free conditions. The reaction proceeded even in the presence of excess water, and excellent functional-group tolerance was observed. Subsequent hydrolysis gave the alcohol in high yields. Moreover, H2O had a critical role in activation of the Co(II) catalyst with hydrosilane. Several additional results also indicated that the cobalt(II) center acts as an active catalyst in the hydrosilylation of aldehydes and ketones.

Nickel-catalyzed reductive deoxygenation of diverse C-O bond-bearing functional groups

Cook, Adam,MacLean, Haydn,St. Onge, Piers,Newman, Stephen G.

, p. 13337 - 13347 (2021/11/20)

We report a catalytic method for the direct deoxygenation of various C-O bond-containing functional groups. Using a Ni(II) pre-catalyst and silane reducing agent, alcohols, epoxides, and ethers are reduced to the corresponding alkane. Unsaturated species including aldehydes and ketones are also deoxygenated via initial formation of an intermediate silylated alcohol. The reaction is chemoselective for C(sp3)-O bonds, leaving amines, anilines, aryl ethers, alkenes, and nitrogen-containing heterocycles untouched. Applications toward catalytic deuteration, benzyl ether deprotection, and the valorization of biomass-derived feedstocks demonstrate some of the practical aspects of this methodology.

Diboron-Mediated Rhodium-Catalysed Transfer Hydrogenation of Alkenes and Carbonyls

Lin, Xiao,Wang, Yuhan,Hu, Yan,Zhu, Wanjiang,Dou, Xiaowei

supporting information, p. 1046 - 1049 (2020/02/25)

A diboron-mediated rhodium-catalysed transfer hydrogenation system using water as the hydrogen donor is developed. In addition to a series of alkenes with good functional group tolerance, this rhodium-based catalytic system also effectively reduces aldehydes and ketones. A plausible mechanism involving the RhI-catalysed hydrogen generation and Rh0-catalysed hydrogenation is proposed for the reaction.

Efficient Transfer Hydrogenation of Ketones using Methanol as Liquid Organic Hydrogen Carrier

Garg, Nidhi,Paira, Soumen,Sundararaju, Basker

, p. 3472 - 3476 (2020/05/29)

Herein, we demonstrate an efficient protocol for transfer hydrogenation of ketones using methanol as practical and useful liquid organic hydrogen carrier (LOHC) under Ir(III) catalysis. Various ketones, including electron-rich/electron-poor aromatic ketones, heteroaromatic and aliphatic ketones, have been efficiently reduced into their corresponding alcohols. Chemoselective reduction of ketones was established in the presence of various other reducible functional groups under mild conditions.

1-D manganese(ii)-terpyridine coordination polymers as precatalysts for hydrofunctionalisation of carbonyl compounds

Johnson, Jahvon,Li, Sihan,Mo, Zixuan,Neary, Michelle C.,Zeng, Haisu,Zhang, Guoqi,Zheng, Shengping

, p. 2610 - 2615 (2020/03/05)

Reductive catalysis with earth-abundant metals is currently of increasing importance and shows potential in replacing precious metal catalysis. In this work, we revealed catalytic hydroboration and hydrosilylation of ketones and aldehydes achieved by a structurally defined manganese(ii) coordination polymer (CP) as a precatalyst under mild conditions. The manganese-catalysed methodology can be applied to a range of functionalized aldehydes and ketones with turnover numbers (TON) of up to 990. Preliminary results on the regioselective catalytic hydrofunctionalization of styrenes by the Mn-CP catalyst are also presented.

Erratum: Redox-Noninnocent Ligand-Supported Vanadium Catalysts for the Chemoselective Reduction of C=X (X = O, N) Functionalities (Journal of the American Chemical Society (2019) 141:38 (15230-15239) DOI: 10.1021/jacs.9b07062)

Zhang, Guoqi,Wu, Jing,Zheng, Shengping,Neary, Michelle C.,Mao, Jincheng,Flores, Marco,Trovitch, Ryan J.,Dub, Pavel A.

, p. 16507 - 16509 (2020/10/14)

Pages 15232, 15233, and 15236. In the original paper, the doublet wave functions for 21 and 21a/21b were incorrectly (Figure Presented). reported as spin-contaminated in sections 2.3 and 2.8 (Figure 3 and Scheme 9, respectively.) This comes from the incorrectly reported expected eigenvalue of 0.75 for the spin-squared operator ??2? for the antiferromagnetically coupled doublet |↓?L|↑↑?V state (originally given in the Supporting Information). The correct expected eigenvalue for the |↓?L|↑↑?V state should be 1.75. The wave functions for 21 and 21a/21b (eigenvalues 1.79 and 1.77/1.66, respectively) are therefore not spincontaminated. The corrected Figure 3 and Scheme 9 are presented below. A corrected Supporting Information file is also provided. The corrections do not affect any of the conclusions of the Article, but slightly decrease the gap between the quartet and doublet spin surfaces. Scheme 3 has been also corrected to reflect the fact that (CH3)3SiCH2 ? radicals can only react based on spin conservation.

Heteroditopic Ru(II)-And Ir(III)-NHC Complexes with Pendant 1,2,3-Triazole/Triazolylidene Groups: Stereoelectronic Impact on Transfer Hydrogenation of Unsaturated Compounds

Illam, Praseetha Mathoor,Donthireddy,Chakrabartty, Sayantan,Rit, Arnab

supporting information, p. 2610 - 2623 (2019/07/31)

Imidazol-2-ylidene (ImNHC) and 1,2,3-Traizol-5-ylidene (tzNHC) have been established as important classes of carbene ligands in homogeneous catalysis. To develop Ru(II)/Ir(III) complexes based on these ligand systems considering their electronic as well as steric profiles for hydride transfer reactions, we employed chelating ligands featuring combinations of ImNHC and triazole-N or mesoionic tzNHC donors bridged by a CH2 spacer with possible modifications at triazole backbone. In general, synthesized Ru(II) complexes were found to perform significantly better than analogous Ir(III) complexes in ketone and aldimine reduction. Among the Ru(II) complexes, electron-rich complexes 8/9 of the general formula [(p-cymene)(ImNHC-CH2-TzNHC)RuII(Cl)]BF4 with two different carbene donors (ImNHC and tzNHC) were found to perform appreciably better in ketone reduction than analogous complexes with a combination of ImNHC and triazole-N-donor ([(p-cymene)(ImNHC-CH2-Tz-N)RuII(Cl)]BF4; 4) explaining the electronic fine-Tuning of the catalytic systems. No appreciable variation in activity was observed between complexes 8 and 9 having almost similar electronic profiles. However, less bulky Ru(II) complex 9 with a triazole N-phenyl substituent is more suitable for aldimine reduction than is complex 8, having a triazole N-3,5-dimethylphenyl substituent that explains the steric influence in addition to electronic effect on the reduction process.

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